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Cellosaurus KYN-1 (CVCL_7925)

[Text version]
Cell line name KYN-1
Synonyms KYN1
Accession CVCL_7925
Resource Identification Initiative To cite this cell line use: KYN-1 (RRID:CVCL_7925)
Comments Population: Japanese.
Doubling time: 10-11 days (Note=At 17th passage) (PubMed=2430933).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
HLA typing Source: PubMed=9178645
Class I
HLA-AA*24:02,24
HLA-BB*54:01
HLA-CC*01:02
Class II
HLA-DQDQA1*03:01
DQB1*04:01
HLA-DRDRB1*04:05
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=2430933; DOI=10.1007/BF02623477
Hirohisa Yano, Masamichi Kojiro, Toshiro Nakashima;
A new human hepatocellular carcinoma cell line (KYN-1) with a transformation to adenocarcinoma.
In Vitro Cell. Dev. Biol. 22:637-646(1986)

PubMed=7537711; DOI=10.1002/hep.1840210510
Makoto Haramaki, Hirohisa Yano, Kazunori Fukuda, Seiya Momosaki, Sachiko Ogasawara, Masamichi Kojiro;
Expression of CD44 in human hepatocellular carcinoma cell lines.
Hepatology 21:1276-1284(1995)

PubMed=9178645; DOI=10.1006/cimm.1997.1108
Masanobu Nakao, Michio Sata, Hideki Saitsu, Shigeru Yutani, Mayumi Kawamoto, Masamichi Kojiro, Kyogo Itoh;
CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma.
Cell. Immunol. 177:176-181(1997)

PubMed=10347112; DOI=10.1002/hep.510290624
Hirohisa Yano, Akihiro Iemura, Makoto Haramaki, Sachiko Ogasawara, Akiko Takayama, Jun Akiba, Masamichi Kojiro;
Interferon alfa receptor expression and growth inhibition by interferon alfa in human liver cancer cell lines.
Hepatology 29:1708-1717(1999)

PubMed=27329724; DOI=10.18632/oncotarget.10161; PMCID=PMC5216950
Kosuke Watari, Ayumi Nishitani, Tomohiro Shibata, Masaki Noda, Akihiko Kawahara, Jun Akiba, Yuichi Murakami, Hirohisa Yano, Michihiko Kuwano, Mayumi Ono;
Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma.
Oncotarget 7:47403-47417(2016)

Cross-references
Encyclopedic resources Wikidata; Q54900789
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number13