Cellosaurus logo
expasy logo

Cellosaurus KYN-1 (CVCL_7925)

[Text version]
Cell line name KYN-1
Synonyms KYN1
Accession CVCL_7925
Resource Identification Initiative To cite this cell line use: KYN-1 (RRID:CVCL_7925)
Comments Population: Japanese.
Doubling time: 10-11 days (Note=At 17th passage) (PubMed=2430933).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
HLA typing Source: PubMed=9178645
Class I
HLA-AA*24:02,24
HLA-BB*54:01
HLA-CC*01:02
Class II
HLA-DQDQA1*03:01
DQB1*04:01
HLA-DRDRB1*04:05
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=2430933; DOI=10.1007/BF02623477
Yano H., Kojiro M., Nakashima T.
A new human hepatocellular carcinoma cell line (KYN-1) with a transformation to adenocarcinoma.
In Vitro Cell. Dev. Biol. 22:637-646(1986)

PubMed=7537711; DOI=10.1002/hep.1840210510
Haramaki M., Yano H., Fukuda K., Momosaki S., Ogasawara S., Kojiro M.
Expression of CD44 in human hepatocellular carcinoma cell lines.
Hepatology 21:1276-1284(1995)

PubMed=9178645; DOI=10.1006/cimm.1997.1108
Nakao M., Sata M., Saitsu H., Yutani S., Kawamoto M., Kojiro M., Itoh K.
CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma.
Cell. Immunol. 177:176-181(1997)

PubMed=10347112; DOI=10.1002/hep.510290624
Yano H., Iemura A., Haramaki M., Ogasawara S., Takayama A., Akiba J., Kojiro M.
Interferon alfa receptor expression and growth inhibition by interferon alfa in human liver cancer cell lines.
Hepatology 29:1708-1717(1999)

PubMed=27329724; DOI=10.18632/oncotarget.10161; PMCID=PMC5216950
Watari K., Nishitani A., Shibata T., Noda M., Kawahara A., Akiba J., Murakami Y., Yano H., Kuwano M., Ono M.
Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma.
Oncotarget 7:47403-47417(2016)

Cross-references
Encyclopedic resources Wikidata; Q54900789
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number13