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Cellosaurus NCC-BD1 (CVCL_7883)

[Text version]
Cell line name NCC-BD1
Accession CVCL_7883
Resource Identification Initiative To cite this cell line use: NCC-BD1 (RRID:CVCL_7883)
Comments Population: Japanese.
Derived from site: In situ; Bile duct; UBERON=UBERON_0002394.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Cys (c.37G>T); ClinVar=VCV000045123; Zygosity=Unspecified (PubMed=20088962).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro153Ser (c.457C>T); ClinVar=VCV000422563; Zygosity=Unspecified (PubMed=20088962).
  • Mutation; HGNC; 11998; TP53; Simple; p.Thr155Pro (c.463A>C); Zygosity=Unspecified (PubMed=20088962).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg156Pro (c.467G>C); ClinVar=VCV000634768; Zygosity=Unspecified (PubMed=20088962).
Disease Cholangiocarcinoma (NCIt: C4436)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): TKG=TKG 0737

Markers:
AmelogeninX
CSF1PO10,11
D5S81810,12
D7S8208,10
D13S3178
D16S5399
TH016
TPOX8,11
vWA16,81

Run an STR similarity search on this cell line
Publications

PubMed=20088962; DOI=10.1111/j.1349-7006.2009.01462.x
Ojima H., Yoshikawa D., Ino Y., Shimizu H., Miyamoto M., Kokubu A., Hiraoka N., Morofuji N., Kondo T., Onaya H., Okusaka T., Shimada K., Sakamoto Y., Esaki M., Nara S., Kosuge T., Hirohashi S., Kanai Y., Shibata T.
Establishment of six new human biliary tract carcinoma cell lines and identification of MAGEH1 as a candidate biomarker for predicting the efficacy of gemcitabine treatment.
Cancer Sci. 101:882-888(2010)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=26141945; DOI=10.1158/1535-7163.MCT-15-0069
Shirota T., Ojima H., Hiraoka N., Shimada K., Rokutan H., Arai Y., Kanai Y., Miyagawa S., Shibata T.
Heat shock protein 90 is a potential therapeutic target in cholangiocarcinoma.
Mol. Cancer Ther. 14:1985-1993(2015)

PubMed=27833395; DOI=10.3748/wjg.v22.i40.9035
Ojima H., Yamagishi S., Shimada K., Shibata T.
Establishment of various biliary tract carcinoma cell lines and xenograft models for appropriate preclinical studies.
World J. Gastroenterol. 22:9035-9038(2016)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line collections (Providers) TKG; TKG 0737
Cell line databases/resources cancercelllines; CVCL_7883
Encyclopedic resources Wikidata; Q54907598
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number18