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Cellosaurus UT-SCC-5 (CVCL_7858)

[Text version]
Cell line name UT-SCC-5
Synonyms UTSCC5; University of Turku-Squamous Cell Carcinoma-5
Accession CVCL_7858
Resource Identification Initiative To cite this cell line use: UT-SCC-5 (RRID:CVCL_7858)
Comments Omics: Transcriptomics; Microarray.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=33802339

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817,22
D3S135816
D5S81810
D7S82010
D8S117913,14
D13S3179,12
D16S53911
D18S5118
D19S43315
D21S1130
FGA22,23
TH017,9.3
TPOX8,12
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=8725545; DOI=10.3109/00016489609137854
Kirsi Pekkola-Heino, Kristina Servomaa, Anne Kiuru, Reidar Grenman;
Increased radiosensitivity is associated with p53 mutations in cell lines derived from oral cavity carcinoma.
Acta Oto-Laryngol. 116:341-344(1996)

PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x
Kristina Servomaa, Anne Kiuru, Reidar Grenman, Kirsi Pekkola-Heino, Jaakko O. Pulkkinen, Tapio Rytomaa;
p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell lines.
Cell Prolif. 29:219-230(1996)

PubMed=11799138; DOI=10.1177/002215540205000207
Wolfgang Eicheler, Daniel Zips, Annegret Dorfler, Reidar Grenman, Michael Baumann;
Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection.
J. Histochem. Cytochem. 50:197-204(2002)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=20429727; DOI=10.3109/02841861003614343
Brita Singers Sorensen, Kasper Toustrup, Michael R. Horsman, Jens Overgaard, Jan Alsner;
Identifying pH independent hypoxia induced genes in human squamous cell carcinomas in vitro.
Acta Oncol. 49:895-905(2010)

PubMed=33802339; DOI=10.3390/cancers13051069; PMCID=PMC7959143
Eva-Leonne Gottgens, Marleen Ansems, William P.J. Leenders, Johan Bussink, Paul N. Span;
Genotyping and characterization of HPV status, hypoxia, and radiosensitivity in 22 head and neck cancer cell lines.
Cancers (Basel) 13:1069.1-1069.12(2021)

Cross-references
Anatomy/cell type resources BTO; BTO_0004442
Encyclopedic resources Wikidata; Q54992143
Gene expression databases GEO; GSM1716431
GEO; GSM1716432
GEO; GSM1716433
GEO; GSM1716434
Polymorphism and mutation databases IARC_TP53; 11069
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number15