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Cellosaurus UT-SCC-4 (CVCL_7844)

[Text version]
Cell line name UT-SCC-4
Synonyms University of Turku-Squamous Cell Carcinoma-4
Accession CVCL_7844
Resource Identification Initiative To cite this cell line use: UT-SCC-4 (RRID:CVCL_7844)
Comments Omics: Transcriptomics; miRNA profiling; Microarray.
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248_Pro250del (c.742_750del9); Zygosity=Unspecified (PubMed=8782485).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x
Kristina Servomaa, Anne Kiuru, Reidar Grenman, Kirsi Pekkola-Heino, Jaakko O. Pulkkinen, Tapio Rytomaa;
p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell lines.
Cell Prolif. 29:219-230(1996)

PubMed=9187133
Tero Soukka, Marko Salmi, Heikki Joensuu, Lan Hakkinen, Petri Sointu, Leena Koulu, Kirsti Kalimo, Pekka Klemi, Reidar Grenman, Sirpa T. Jalkanen;
Regulation of CD44v6-containing isoforms during proliferation of normal and malignant epithelial cells.
Cancer Res. 57:2281-2289(1997)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=26694163; DOI=10.1371/journal.pone.0144924; PMCID=PMC4692263
Joanna Janiszewska, Marcin Szaumkessel, Magdalena Kostrzewska-Poczekaj, Kinga Bednarek, Julia Paczkowska, Joanna Jackowska, Reidar Grenman, Krzysztof Szyfter, Malgorzata Wierzbicka, Maciej Giefing, Malgorzata Jarmuz-Szymczak;
Global miRNA expression profiling identifies miR-1290 as novel potential oncomiR in laryngeal carcinoma.
PLoS ONE 10:e0144924.1-e0144924.13(2015)

Cross-references
Encyclopedic resources Wikidata; Q54992125
Polymorphism and mutation databases IARC_TP53; 11060
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number14