ID   UT-SCC-4
AC   CVCL_7844
SY   University of Turku-Squamous Cell Carcinoma-4
DR   IARC_TP53; 11060
DR   Wikidata; Q54992125
RX   PubMed=8782485;
RX   PubMed=9187133;
RX   PubMed=17312569;
RX   PubMed=26694163;
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248_Pro250del (c.742_750del9); Zygosity=Unspecified (PubMed=8782485).
CC   Omics: miRNA expression profiling.
CC   Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   43Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 12
//
RX   PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x;
RA   Servomaa K., Kiuru A., Grenman R., Pekkola-Heino K., Pulkkinen J.O.,
RA   Rytomaa T.;
RT   "p53 mutations associated with increased sensitivity to ionizing
RT   radiation in human head and neck cancer cell lines.";
RL   Cell Prolif. 29:219-230(1996).
//
RX   PubMed=9187133;
RA   Soukka T., Salmi M., Joensuu H., Hakkinen L., Sointu P., Koulu L.,
RA   Kalimo K., Klemi P., Grenman R., Jalkanen S.T.;
RT   "Regulation of CD44v6-containing isoforms during proliferation of
RT   normal and malignant epithelial cells.";
RL   Cancer Res. 57:2281-2289(1997).
//
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
//
RX   PubMed=26694163; DOI=10.1371/journal.pone.0144924;
RA   Janiszewska J., Szaumkessel M., Kostrzewska-Poczekaj M., Bednarek K.,
RA   Paczkowska J., Jackowska J., Grenman R., Szyfter K., Wierzbicka M.,
RA   Giefing M., Jarmuz-Szymczak M.;
RT   "Global miRNA expression profiling identifies miR-1290 as novel
RT   potential oncomiR in laryngeal carcinoma.";
RL   PLoS ONE 10:E0144924-E0144924(2015).
//