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Cellosaurus UT-SCC-24B (CVCL_7827)

[Text version]
Cell line name UT-SCC-24B
Synonyms UT-SCC-24b; UT-SCC 24B; University of Turku-Squamous Cell Carcinoma-24B
Accession CVCL_7827
Resource Identification Initiative To cite this cell line use: UT-SCC-24B (RRID:CVCL_7827)
Comments Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.673-2A>T (IVS6-2A>T); ClinVar=VCV000635388; Zygosity=Unspecified; Note=Splice acceptor mutation (PubMed=11799138).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7826 ! UT-SCC-24A
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
Publications

PubMed=8725545; DOI=10.3109/00016489609137854
Kirsi Pekkola-Heino, Kristina Servomaa, Anne Kiuru, Reidar Grenman;
Increased radiosensitivity is associated with p53 mutations in cell lines derived from oral cavity carcinoma.
Acta Oto-Laryngol. 116:341-344(1996)

PubMed=11799138; DOI=10.1177/002215540205000207
Wolfgang Eicheler, Daniel Zips, Annegret Dorfler, Reidar Grenman, Michael Baumann;
Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection.
J. Histochem. Cytochem. 50:197-204(2002)

PubMed=16331601; DOI=10.1002/ijc.21514
Anja Muller, Eniko Sonkoly, Christine Eulert, Peter Arne Gerber, Robert Kubitza, Kerstin Schirlau, Petra Franken-Kunkel, Christopher Poremba, Carl Henry Snyderman, Lars-Oliver Klotz, Thomas Ruzicka ...Show all 16 authors... , Henning Bier, Albert Zlotnik, Theresa L. Whiteside, Bernhard Homey, Thomas K. Hoffmann; Show fewer authors
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Int. J. Cancer 118:2147-2157(2006)

PubMed=17312569; DOI=10.1002/hed.20478
Charles J. Lin, Jennifer Rubin Grandis, Thomas E. Carey, Susanne M. Gollin, Theresa L. Whiteside, Wayne M. Koch, Robert Louis Ferris, Stephen Y. Lai;
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=18487078; DOI=10.1016/j.oraloncology.2008.02.006
Thomas K. Hoffmann, Eniko Sonkoly, Ulrich Hauser, Anke van Lierop, Theresa L. Whiteside, Jens Peter Klussmann, Dieter Hafner, Patrick J. Schuler, Ulrike Friebe-Hoffmann, Kathrin Scheckenbach, Kaisa Erjala ...Show all 15 authors... , Reidar Grenman, Jorg Schipper, Henning Bier, Vera Balz; Show fewer authors
Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma.
Oral Oncol. 44:1100-1109(2008)

DOI=10.1158/1538-7445.AM2020-507
Maria K. Kondratyev, Aleksandra Pesic, Anna Dvorkin-Sheva, Troy Ketela, Jason Moffat, Marianne Koritzinsky, Bradly G. Wouters;
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Encyclopedic resources Wikidata; Q54992104
Polymorphism and mutation databases IARC_TP53; 17655
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18