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Cellosaurus UT-SCC-11 (CVCL_7805)

[Text version]
Cell line name UT-SCC-11
Synonyms UTSCC11; University of Turku-Squamous Cell Carcinoma-11
Accession CVCL_7805
Resource Identification Initiative To cite this cell line use: UT-SCC-11 (RRID:CVCL_7805)
Comments Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; miRNA profiling; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Larynx, glottis; UBERON=UBERON_0002486.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly187_Arg196del (c.560_589del); Zygosity=Unspecified (PubMed=33802339).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=33802339

Markers:
AmelogeninX,Y
CSF1PO10
D2S133819,20
D3S135817
D5S81813
D7S8209,11
D8S117912
D13S3179,11
D16S5399,11
D18S5115,17
D19S43313,14
D21S1128
FGA22,23
TH016,9
TPOX9,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=9187133
Soukka T., Salmi M., Joensuu H., Hakkinen L., Sointu P., Koulu L., Kalimo K., Klemi P., Grenman R., Jalkanen S.T.
Regulation of CD44v6-containing isoforms during proliferation of normal and malignant epithelial cells.
Cancer Res. 57:2281-2289(1997)

PubMed=16715129; DOI=10.1038/sj.onc.1209690
Jarvinen A.-K., Autio R., Haapa-Paananen S., Wolf M., Saarela M., Grenman R., Leivo I., Kallioniemi O.-P., Makitie A.A., Monni O.
Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses.
Oncogene 25:6997-7008(2006)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=26694163; DOI=10.1371/journal.pone.0144924; PMCID=PMC4692263
Janiszewska J., Szaumkessel M., Kostrzewska-Poczekaj M., Bednarek K., Paczkowska J., Jackowska J., Grenman R., Szyfter K., Wierzbicka M., Giefing M., Jarmuz-Szymczak M.
Global miRNA expression profiling identifies miR-1290 as novel potential oncomiR in laryngeal carcinoma.
PLoS ONE 10:e0144924.1-e0144924.13(2015)

PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733
Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A., Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M., Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O.
Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy.
Mol. Cancer Ther. 17:2060-2071(2018)

PubMed=33802339; DOI=10.3390/cancers13051069; PMCID=PMC7959143
Gottgens E.-L., Ansems M., Leenders W.P.J., Bussink J., Span P.N.
Genotyping and characterization of HPV status, hypoxia, and radiosensitivity in 22 head and neck cancer cell lines.
Cancers (Basel) 13:1069.1-1069.12(2021)

Cross-references
Encyclopedic resources Wikidata; Q54992056
Gene expression databases GEO; GSM2883358
GEO; GSM2888821
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number14