ID   UT-SCC-11
AC   CVCL_7805
SY   UTSCC11; University of Turku-Squamous Cell Carcinoma-11
DR   GEO; GSM2883358
DR   GEO; GSM2888821
DR   Wikidata; Q54992056
RX   PubMed=9187133;
RX   PubMed=16715129;
RX   PubMed=17312569;
RX   PubMed=26694163;
RX   PubMed=29970484;
RX   PubMed=33802339;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly187_Arg196del (c.560_589del); Zygosity=Unspecified (PubMed=33802339).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; miRNA profiling; Microarray.
CC   Omics: Variations; Array-based CGH.
CC   Derived from site: In situ; Larynx, glottis; UBERON=UBERON_0002486.
ST   Source(s): PubMed=33802339
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 9,11
ST   D16S539: 9,11
ST   D18S51: 15,17
ST   D19S433: 13,14
ST   D21S11: 28
ST   D2S1338: 19,20
ST   D3S1358: 17
ST   D5S818: 13
ST   D7S820: 9,11
ST   D8S1179: 12
ST   FGA: 22,23
ST   TH01: 6,9
ST   TPOX: 9,11
ST   vWA: 16,17
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 14
//
RX   PubMed=9187133;
RA   Soukka T., Salmi M., Joensuu H., Hakkinen L., Sointu P., Koulu L.,
RA   Kalimo K., Klemi P., Grenman R., Jalkanen S.T.;
RT   "Regulation of CD44v6-containing isoforms during proliferation of
RT   normal and malignant epithelial cells.";
RL   Cancer Res. 57:2281-2289(1997).
//
RX   PubMed=16715129; DOI=10.1038/sj.onc.1209690;
RA   Jarvinen A.-K., Autio R., Haapa-Paananen S., Wolf M., Saarela M.,
RA   Grenman R., Leivo I., Kallioniemi O.-P., Makitie A.A., Monni O.;
RT   "Identification of target genes in laryngeal squamous cell carcinoma
RT   by high-resolution copy number and gene expression microarray
RT   analyses.";
RL   Oncogene 25:6997-7008(2006).
//
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
//
RX   PubMed=26694163; DOI=10.1371/journal.pone.0144924; PMCID=PMC4692263;
RA   Janiszewska J., Szaumkessel M., Kostrzewska-Poczekaj M., Bednarek K.,
RA   Paczkowska J., Jackowska J., Grenman R., Szyfter K., Wierzbicka M.,
RA   Giefing M., Jarmuz-Szymczak M.;
RT   "Global miRNA expression profiling identifies miR-1290 as novel
RT   potential oncomiR in laryngeal carcinoma.";
RL   PLoS ONE 10:e0144924.1-e0144924.13(2015).
//
RX   PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733;
RA   Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A.,
RA   Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M.,
RA   Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O.;
RT   "Drug-sensitivity screening and genomic characterization of 45
RT   HPV-negative head and neck carcinoma cell lines for novel biomarkers
RT   of drug efficacy.";
RL   Mol. Cancer Ther. 17:2060-2071(2018).
//
RX   PubMed=33802339; DOI=10.3390/cancers13051069; PMCID=PMC7959143;
RA   Gottgens E.-L., Ansems M., Leenders W.P.J., Bussink J., Span P.N.;
RT   "Genotyping and characterization of HPV status, hypoxia, and
RT   radiosensitivity in 22 head and neck cancer cell lines.";
RL   Cancers (Basel) 13:1069.1-1069.12(2021).
//