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Cellosaurus PR-GTL-16 (CVCL_7696)

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Cell line name PR-GTL-16
Accession CVCL_7696
Resource Identification Initiative To cite this cell line use: PR-GTL-16 (RRID:CVCL_7696)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_90197; PHA-665752.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7668 (GTL-16)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=21208906; DOI=10.1158/1078-0432.CCR-10-0253; PMCID=PMC3263825
Thomas Bachleitner-Hofmann, Mark Y. Sun, Chin-Tung Chen, David Liska, Zhao-Shi Zeng, Agnes J. Viale, Adam B. Olshen, Martina Mittlbock, James Gail Christensen, Neal Rosen, David B. Solit, Martin R. Weiser;
Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET Inhibition.
Clin. Cancer Res. 17:122-133(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7696
Encyclopedic resources Wikidata; Q54947819
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number19