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Cellosaurus HOSE 6-3 (CVCL_7673)

[Text version]
Cell line name HOSE 6-3
Synonyms HOSE6-3; Human Ovarian Surface Epithelial cells 6-3
Accession CVCL_7673
Resource Identification Initiative To cite this cell line use: HOSE 6-3 (RRID:CVCL_7673)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=7796885; DOI=10.1006/excr.1995.1184
George Sai-Wah Tsao, Samuel C. Mok, Edward G. Fey, Jonathan A. Fletcher, Thomas Shek-Kong Wan, Eng-Ching Chew, Michael G. Muto, Robert C. Knapp, Ross Stuart Berkowitz;
Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs).
Exp. Cell Res. 218:499-507(1995)

PubMed=11675135; DOI=10.1016/S0165-4608(01)00473-3
George Sai-Wah Tsao, Nathalie Wong, Xiang-Hong Wang, Yu Liu, Thomas Shek-Kong Wan, Lai-Fan Fung, Wayne D. Lancaster, Lucie Gregoire, Yong-Chuan Wong;
Nonrandom chromosomal imbalances in human ovarian surface epithelial cells immortalized by HPV16-E6E7 viral oncogenes.
Cancer Genet. Cytogenet. 130:141-149(2001)

PubMed=15489894; DOI=10.1038/sj.onc.1208119
Wen Deng, George Sai-Wah Tsao, Xin-Yuan Guan, Joe N. Lucas, Hua-Xin Si, Chi-Shing Leung, Priscilla Mak, Li-Dong Wang, Annie Lai-Man Cheung;
Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines.
Oncogene 23:9090-9101(2004)

Cross-references
Anatomy/cell type resources BTO; BTO_0004436
Encyclopedic resources Wikidata; Q54890181
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number19