ID   HOSE 6-3
AC   CVCL_7673
SY   HOSE6-3; Human Ovarian Surface Epithelial cells 6-3
DR   BTO; BTO_0004436
DR   Wikidata; Q54890181
RX   PubMed=7796885;
RX   PubMed=11675135;
RX   PubMed=15489894;
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 18
//
RX   PubMed=7796885; DOI=10.1006/excr.1995.1184;
RA   Tsao S.-W., Mok S.C., Fey E.G., Fletcher J.A., Wan T.S.-K., Chew E.-C.,
RA   Muto M.G., Knapp R.C., Berkowitz R.S.;
RT   "Characterization of human ovarian surface epithelial cells
RT   immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs).";
RL   Exp. Cell Res. 218:499-507(1995).
//
RX   PubMed=11675135; DOI=10.1016/S0165-4608(01)00473-3;
RA   Tsao S.-W., Wong N., Wang X.-H., Liu Y., Wan T.S.-K., Fung L.-F.,
RA   Lancaster W.D., Gregoire L., Wong Y.-C.;
RT   "Nonrandom chromosomal imbalances in human ovarian surface epithelial
RT   cells immortalized by HPV16-E6E7 viral oncogenes.";
RL   Cancer Genet. Cytogenet. 130:141-149(2001).
//
RX   PubMed=15489894; DOI=10.1038/sj.onc.1208119;
RA   Deng W., Tsao S.-W., Guan X.-Y., Lucas J.N., Si H.-X., Leung C.-S.,
RA   Mak P., Wang L.-D., Cheung A.L.-M.;
RT   "Distinct profiles of critically short telomeres are a key determinant
RT   of different chromosome aberrations in immortalized human cells:
RT   whole-genome evidence from multiple cell lines.";
RL   Oncogene 23:9090-9101(2004).
//