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Cellosaurus Panc 06.03 (CVCL_7665)

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Cell line name Panc 06.03
Synonyms Panc-06.03; Panc 6.03; PANC 6.03; Panc6.03; Pa19C; Pa019C
Accession CVCL_7665
Resource Identification Initiative To cite this cell line use: Panc 06.03 (RRID:CVCL_7665)
Comments Problematic cell line: Contaminated. Panc 01.28, Panc 04.21 and Panc 06.03 have been shown to be identical (on the basis of STR profile).
From: Johns Hopkins University School of Medicine; Baltimore; USA.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00521.
Doubling time: 34.0 hours (PubMed=9612602).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (ATCC=CRL-2550).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7666 ! Panc 01.28
CVCL_7664 ! Panc 04.21
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2550

Markers:
AmelogeninX
CSF1PO11
D5S81811,12
D7S82010,12
D13S3178,11
D16S53911,12
TH016,9.3
TPOX9,11
vWA16,17

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=9612602
Elizabeth Marion Jaffee, Mieke Schutte, Jeanette Gossett, Laura A. Morsberger, Adam J. Adler, Matthew Thomas, Tim F. Greten, Ralph H. Hruban, Charles J. Yeo, Constance A. Griffin;
Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials.
Cancer J. Sci. Am. 4:194-203(1998)

PubMed=14695172
Christine A. Iacobuzio-Donahue, Raheela Ashfaq, Anirban Maitra, Nazmi Volkan Adsay, Grace L.-C. Shen-Ong, Karin Berg, Michael Anthony Hollingsworth, John Lemuel Cameron, Charles J. Yeo, Scott E. Kern, Michael Gilbert Goggins, Ralph H. Hruban;
Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies.
Cancer Res. 63:8614-8622(2003)

PubMed=18000365; DOI=10.1159/000108295
Constance A. Griffin, Laura A. Morsberger, Anita L. Hawkins, Mary H. Haddadin, Ankita S. Patel, Thomas Ried, Evelin Schrock, Elizabeth J. Perlman, Elizabeth Marion Jaffee;
Molecular cytogenetic characterization of pancreas cancer cell lines reveals high complexity chromosomal alterations.
Cytogenet. Genome Res. 118:148-156(2007)

PubMed=22753594; DOI=10.1158/1078-0432.CCR-12-0827; PMCID=PMC3513499
Yun-Feng Cui, Jacqueline A. Brosnan-Cashman, Amanda L. Blackford, Surojit Sur, Ralph H. Hruban, Kenneth Wayne Kinzler, Bert Vogelstein, Anirban Maitra, Luis Alberto Diaz Jr., Christine A. Iacobuzio-Donahue, James Richard Eshleman;
Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity.
Clin. Cancer Res. 18:6519-6530(2012)

Cross-references
Cell line collections (Providers) ATCC; CRL-2550 - Discontinued
Cell line databases/resources cancercelllines; CVCL_7665
Biological sample resources BioSample; SAMN06481122
Encyclopedic resources Wikidata; Q54937527
Polymorphism and mutation databases Cosmic; 1473096
Cosmic; 1509873
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number25