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Cellosaurus Panc 06.03 (CVCL_7665)

[Text version]
Cell line name Panc 06.03
Synonyms Panc-06.03; Panc 6.03; PANC 6.03; Panc6.03; Pa19C; Pa019C
Accession CVCL_7665
Resource Identification Initiative To cite this cell line use: Panc 06.03 (RRID:CVCL_7665)
Comments Problematic cell line: Contaminated. Panc 01.28, Panc 04.21 and Panc 06.03 have been shown to be identical (on the basis of STR profile).
From: Johns Hopkins University School of Medicine; Baltimore; USA.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00521.
Doubling time: 34.0 hours (PubMed=9612602).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (ATCC=CRL-2550).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7666 ! Panc 01.28
CVCL_7664 ! Panc 04.21
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2550


Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx

Jaffee E.M., Schutte M., Gossett J., Morsberger L.A., Adler A.J., Thomas M., Greten T.F., Hruban R.H., Yeo C.J., Griffin C.A.
Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials.
Cancer J. Sci. Am. 4:194-203(1998)

Iacobuzio-Donahue C.A., Ashfaq R., Maitra A., Adsay N.V., Shen-Ong G.L.-C., Berg K., Hollingsworth M.A., Cameron J.L., Yeo C.J., Kern S.E., Goggins M.G., Hruban R.H.
Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies.
Cancer Res. 63:8614-8622(2003)

PubMed=18000365; DOI=10.1159/000108295
Griffin C.A., Morsberger L.A., Hawkins A.L., Haddadin M.H., Patel A.S., Ried T., Schrock E., Perlman E.J., Jaffee E.M.
Molecular cytogenetic characterization of pancreas cancer cell lines reveals high complexity chromosomal alterations.
Cytogenet. Genome Res. 118:148-156(2007)

PubMed=22753594; DOI=10.1158/1078-0432.CCR-12-0827
Cui Y.-F., Brosnan-Cashman J.A., Blackford A.L., Sur S., Hruban R.H., Kinzler K.W., Vogelstein B., Maitra A., Diaz L.A. Jr., Iacobuzio-Donahue C.A., Eshleman J.R.
Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity.
Clin. Cancer Res. 18:6519-6530(2012)

Cell line collections (Providers) ATCC; CRL-2550 - Discontinued
Cell line databases/resources cancercelllines; CVCL_7665
Biological sample resources BioSample; SAMN06481122
Encyclopedic resources Wikidata; Q54937527
Polymorphism and mutation databases Cosmic; 1473096
Cosmic; 1509873
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number23