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Cellosaurus GM00316 (CVCL_7278)

[Text version]
Cell line name GM00316
Synonyms GM-316; GM 316; GM316; GM00316A; GM0316A; GM00316B; GM0316B
Accession CVCL_7278
Resource Identification Initiative To cite this cell line use: GM00316 (RRID:CVCL_7278)
Comments Population: Caucasian.
Senescence: Senesces at 22 PDL (PubMed=6492896).
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 12Y
Category Finite cell line
Publications

PubMed=180603; DOI=10.1126/science.180603
David W. Martin Jr., Bonnie A. Maler;
Phosphoribosylpyrophosphate synthetase is elevated in fibroblasts from patients with the Lesch-Nyhan syndrome.
Science 193:408-411(1976)

DOI=10.5962/bhl.title.4090
Lewis Lemon Coriell, Arthur E. Greene;
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 4th edition. October 1977.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda; USA (1977)

CLPUB00387
Lewis Lemon Coriell, Arthur E. Greene, Richard A. Mulivor;
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 7th edition. October 1980.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 80-2011; pp.1-254; National Institutes of Health; Bethesda; USA (1980)

PubMed=7301938; DOI=10.1111/j.1751-1097.1981.tb09049.x
Rufus S. Day 3rd, Chuck H.J. Ziolkowski, Michael DiMattina;
Decreased host cell reactivation of UV-irradiated adenovirus 5 by fibroblasts from Cockayne's syndrome patients.
Photochem. Photobiol. 34:603-607(1981)

PubMed=6492896; DOI=10.1016/0047-6374(84)90044-7
James Edward Cleaver;
DNA repair deficiencies and cellular senescence are unrelated in xeroderma pigmentosum cell lines.
Mech. Ageing Dev. 27:189-196(1984)

PubMed=2987007; DOI=10.1016/0014-4827(85)90437-9
John Patrick Murnane, Lloyd F. Fuller, Robert Blair Painter;
Establishment and characterization of a permanent pSV ori-transformed ataxia-telangiectasia cell line.
Exp. Cell Res. 158:119-126(1985)

CLPUB00720
Arthur E. Greene, Richard A. Mulivor;
1986/1987 catalog of cell lines. NIGMS human genetic mutant cell repository. 13th edition. October 1986.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 87-2011; pp.1-549; National Institutes of Health; Bethesda; USA (1986)

CLPUB00447
Richard A. Mulivor, Sharon F. Suchy;
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992)

PubMed=12665480; DOI=10.1096/fj.02-0851com
Jing-Sheng Tuo, Pawel Jaruga, Henry Rodriguez, Vilhelm A. Bohr, Miral Dizdaroglu;
Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress.
FASEB J. 17:668-674(2003)

PubMed=15268757; DOI=10.1111/j.1474-9728.2004.00105.x
Antonei Benjamin Csoka, Sangeeta B. English, Carl P. Simkevich, David G. Ginzinger, Atul Janardhan Butte, Gerald P. Schatten, Frank G. Rothman, John Michael Sedivy;
Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis.
Aging Cell 3:235-243(2004)

PubMed=19896956; DOI=10.1016/j.mrfmmm.2009.10.013
Paul F. Wilson, Peter B. Nham, Salustra S. Urbin, John M. Hinz, Irene M. Jones, Lawrence H. Thompson;
Inter-individual variation in DNA double-strand break repair in human fibroblasts before and after exposure to low doses of ionizing radiation.
Mutat. Res. 683:91-97(2010)

PubMed=30567591; DOI=10.1186/s13059-018-1599-6; PMCID=PMC6300908
Jason G. Fleischer, Roberta Schulte, Hsiao H. Tsai, Swati Tyagi, Arkaitz Ibarra, Maxim N. Shokhirev, Ling Huang, Martin W. Hetzer, Saket Navlakha;
Predicting age from the transcriptome of human dermal fibroblasts.
Genome Biol. 19:221.1-221.8(2018)

Cross-references
Cell line collections (Providers) Coriell; GM00316 - Discontinued
Cell line databases/resources CLO; CLO_0025545
Encyclopedic resources Wikidata; Q54836154
Gene expression databases GEO; GSM88292
GEO; GSM88293
GEO; GSM88294
GEO; GSM88310
GEO; GSM88311
GEO; GSM88312
GEO; GSM3124640
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number20