ID   GM00316
AC   CVCL_7278
SY   GM-316; GM 316; GM316; GM00316A; GM0316A; GM00316B; GM0316B
DR   CLO; CLO_0025545
DR   Coriell; GM00316
DR   GEO; GSM88292
DR   GEO; GSM88310
DR   GEO; GSM88293
DR   GEO; GSM88311
DR   GEO; GSM88294
DR   GEO; GSM88312
DR   GEO; GSM3124640
DR   Wikidata; Q54836154
RX   CelloPub=CLPUB00387;
RX   CelloPub=CLPUB00447;
RX   CelloPub=CLPUB00720;
RX   DOI=10.5962/bhl.title.4090;
RX   PubMed=180603;
RX   PubMed=2987007;
RX   PubMed=6492896;
RX   PubMed=7301938;
RX   PubMed=12665480;
RX   PubMed=15268757;
RX   PubMed=19896956;
RX   PubMed=30567591;
CC   Population: Caucasian.
CC   Senescence: Senesces at 22 PDL (PubMed=6492896).
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Discontinued: Coriell; GM00316; probable.
CC   Derived from site: In situ; Arm, skin; UBERON=UBERON_0002427.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   12Y
CA   Finite cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 19
//
RX   CelloPub=CLPUB00387;
RA   Coriell L.L., Greene A.E., Mulivor R.A.;
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 7th edition. October 1980.";
RL   (In) Institute for Medical Research (Camden, N.J.) NIH 80-2011; pp.1-254; National Institutes of Health; Bethesda (1980).
//
RX   CelloPub=CLPUB00447;
RA   Mulivor R.A., Suchy S.F.;
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992).
//
RX   CelloPub=CLPUB00720;
RA   Greene A.E., Mulivor R.A.;
RT   "1986/1987 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 13th edition. October 1986.";
RL   (In) Institute for Medical Research (Camden, N.J.) NIH 87-2011; pp.1-549; National Institutes of Health; Bethesda (1986).
//
RX   DOI=10.5962/bhl.title.4090;
RA   Coriell L.L., Greene A.E.;
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 4th edition. October 1977.";
RL   (In) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda (1977).
//
RX   PubMed=180603; DOI=10.1126/science.180603;
RA   Martin D.W. Jr., Maler B.A.;
RT   "Phosphoribosylpyrophosphate synthetase is elevated in fibroblasts
RT   from patients with the Lesch-Nyhan syndrome.";
RL   Science 193:408-411(1976).
//
RX   PubMed=2987007; DOI=10.1016/0014-4827(85)90437-9;
RA   Murnane J.P., Fuller L.F., Painter R.B.;
RT   "Establishment and characterization of a permanent pSV ori-transformed
RT   ataxia-telangiectasia cell line.";
RL   Exp. Cell Res. 158:119-126(1985).
//
RX   PubMed=6492896; DOI=10.1016/0047-6374(84)90044-7;
RA   Cleaver J.E.;
RT   "DNA repair deficiencies and cellular senescence are unrelated in
RT   xeroderma pigmentosum cell lines.";
RL   Mech. Ageing Dev. 27:189-196(1984).
//
RX   PubMed=7301938; DOI=10.1111/j.1751-1097.1981.tb09049.x;
RA   Day R.S. III, Ziolkowski C.H.J., DiMattina M.;
RT   "Decreased host cell reactivation of UV-irradiated adenovirus 5 by
RT   fibroblasts from Cockayne's syndrome patients.";
RL   Photochem. Photobiol. 34:603-607(1981).
//
RX   PubMed=12665480; DOI=10.1096/fj.02-0851com;
RA   Tuo J.-S., Jaruga P., Rodriguez H., Bohr V.A., Dizdaroglu M.;
RT   "Primary fibroblasts of Cockayne syndrome patients are defective in
RT   cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting
RT   from oxidative stress.";
RL   FASEB J. 17:668-674(2003).
//
RX   PubMed=15268757; DOI=10.1111/j.1474-9728.2004.00105.x;
RA   Csoka A.B., English S.B., Simkevich C.P., Ginzinger D.G., Butte A.J.,
RA   Schatten G.P., Rothman F.G., Sedivy J.M.;
RT   "Genome-scale expression profiling of Hutchinson-Gilford progeria
RT   syndrome reveals widespread transcriptional misregulation leading to
RT   mesodermal/mesenchymal defects and accelerated atherosclerosis.";
RL   Aging Cell 3:235-243(2004).
//
RX   PubMed=19896956; DOI=10.1016/j.mrfmmm.2009.10.013;
RA   Wilson P.F., Nham P.B., Urbin S.S., Hinz J.M., Jones I.M.,
RA   Thompson L.H.;
RT   "Inter-individual variation in DNA double-strand break repair in human
RT   fibroblasts before and after exposure to low doses of ionizing
RT   radiation.";
RL   Mutat. Res. 683:91-97(2010).
//
RX   PubMed=30567591; DOI=10.1186/s13059-018-1599-6;
RA   Fleischer J.G., Schulte R., Tsai H.H., Tyagi S., Ibarra A.,
RA   Shokhirev M.N., Huang L., Hetzer M.W., Navlakha S.;
RT   "Predicting age from the transcriptome of human dermal fibroblasts.";
RL   Genome Biol. 19:221.1-221.8(2018).
//