Cell line name |
U-1285 |
Synonyms |
U1285; 1285 |
Accession |
CVCL_7153 |
Resource Identification Initiative |
To cite this cell line use: U-1285 (RRID:CVCL_7153) |
Comments |
Doubling time: 80-84 hours (PubMed=6285665). Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. |
Sequence variations |
- Mutation; HGNC; HGNC:11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Unspecified; Note=Splice acceptor mutation (PubMed=12820372).
|
Disease |
Lung small cell carcinoma (NCIt: C4917) Small cell lung cancer (ORDO: Orphanet_70573) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Children:
|
Sex of cell |
Male |
Age at sampling |
61Y |
Category |
Cancer cell line |
Publications | PubMed=6285665; DOI=10.1111/j.1699-0463.1982.tb00076_90A.x Jonas Bergh, Erik Larsson, Lore Zech, Kenneth Nilsson; Establishment and characterization of two neoplastic cell lines (U-1285 and U-1568) derived from small cell carcinoma of the lung. Acta Pathol. Microbiol. Immunol. Scand. A. 90:149-158(1982) PubMed=2983887 Kalle Martti Saksela, Jonas Bergh, Veli-Pekka Lehto, Kenneth Nilsson, Kari Alitalo; Amplification of the c-myc oncogene in a subpopulation of human small cell lung cancer. Cancer Res. 45:1823-1827(1985) PubMed=12820372 Michael Bergqvist, Daniel Brattstrom, Joachim Gullbo, Patrik Hesselius, Ola Brodin, Gunnar Wagenius; p53 status and its in vitro relationship to radiosensitivity and chemosensitivity in lung cancer. Anticancer Res. 23:1207-1212(2003) PubMed=21508355 Mattias Hedman, Michael Bergqvist, Daniel Brattstrom, Ola Brodin; Fractionated irradiation of five human lung cancer cell lines and prediction of survival according to a radiobiology model. Anticancer Res. 31:1125-1130(2011) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_7153
|
Anatomy/cell type resources |
BTO; BTO_0002389
|
Encyclopedic resources |
Wikidata; Q54973511
|
Polymorphism and mutation databases |
IARC_TP53; 18697
|
Entry history |
Entry creation | 04-Apr-2012 |
Last entry update | 19-Dec-2024 |
Version number | 15 |
---|