ID   U-1285
AC   CVCL_7153
SY   U1285; 1285
DR   BTO; BTO_0002389
DR   cancercelllines; CVCL_7153
DR   IARC_TP53; 18697
DR   Wikidata; Q54973511
RX   PubMed=2983887;
RX   PubMed=6285665;
RX   PubMed=12820372;
RX   PubMed=21508355;
CC   Doubling time: 80-84 hours (PubMed=6285665).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Unspecified; Note=Splice acceptor mutation (PubMed=12820372).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   61Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 15
//
RX   PubMed=2983887;
RA   Saksela K.M., Bergh J., Lehto V.-P., Nilsson K., Alitalo K.;
RT   "Amplification of the c-myc oncogene in a subpopulation of human small
RT   cell lung cancer.";
RL   Cancer Res. 45:1823-1827(1985).
//
RX   PubMed=6285665; DOI=10.1111/j.1699-0463.1982.tb00076_90A.x;
RA   Bergh J., Larsson E., Zech L., Nilsson K.;
RT   "Establishment and characterization of two neoplastic cell lines (U-1285
RT   and U-1568) derived from small cell carcinoma of the lung.";
RL   Acta Pathol. Microbiol. Immunol. Scand. A. 90:149-158(1982).
//
RX   PubMed=12820372;
RA   Bergqvist M., Brattstrom D., Gullbo J., Hesselius P., Brodin O.,
RA   Wagenius G.;
RT   "p53 status and its in vitro relationship to radiosensitivity and
RT   chemosensitivity in lung cancer.";
RL   Anticancer Res. 23:1207-1212(2003).
//
RX   PubMed=21508355;
RA   Hedman M., Bergqvist M., Brattstrom D., Brodin O.;
RT   "Fractionated irradiation of five human lung cancer cell lines and
RT   prediction of survival according to a radiobiology model.";
RL   Anticancer Res. 31:1125-1130(2011).
//