Cellosaurus logo
expasy logo

Cellosaurus PC-10 (CVCL_7088)

[Text version]
Cell line name PC-10
Synonyms PC 10; PC10
Accession CVCL_7088
Resource Identification Initiative To cite this cell line use: PC-10 (RRID:CVCL_7088)
Comments From: Immuno-Biological Laboratories (IBL); Tokyo; Japan.
Population: Japanese.
Sequence variations
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=758928; DOI=10.1038/bjc.1979.3; PMCID=PMC2009802
Mitsuru Kinjo, Kazunari Oka, S. Naito, Shin Kohga, Kenzo Tanaka, Shoichi Oboshi, Yoshihiro Hayata, Kosei Yasumoto;
Thromboplastic and fibrinolytic activities of cultured human cancer cell lines.
Br. J. Cancer 39:15-23(1979)

PubMed=3731100
Nobuo Hanai, Kenya Shitara, Hajime Yoshida;
Generation of monoclonal antibodies against human lung squamous cell carcinoma and adenocarcinoma using mice rendered tolerant to normal human lung.
Cancer Res. 46:4438-4443(1986)

PubMed=8385084; DOI=10.1111/j.1349-7006.1993.tb02851.x; PMCID=PMC5919128
Susumu Suzuki, Takashi Takahashi, Shigeo Nakamura, Koichi Koike, Yutaka Ariyoshi, Toshitada Takahashi, Ryuzo Ueda;
Alterations of integrin expression in human lung cancer.
Jpn. J. Cancer Res. 84:168-174(1993)

PubMed=8263009; DOI=10.1007/BF01202192
Tatsuhiko Kashii, Yutaka Mizushima, Satoshi Monno, K. Nakagawa, M. Kobayashi;
Gene analysis of K-, H-ras, p53, and retinoblastoma susceptibility genes in human lung cancer cell lines by the polymerase chain reaction/single-strand conformation polymorphism method.
J. Cancer Res. Clin. Oncol. 120:143-148(1994)

PubMed=10536175; DOI=10.3892/ijo.15.5.927
Takeshi Fujita, Masaharu Kiyama, Yoshio Tomizawa, Takashi Kohno, Jun Yokota;
Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes.
Int. J. Oncol. 15:927-934(1999)

PubMed=11005564; DOI=10.1038/sj.neo.7900094; PMCID=PMC1550293
Takashi Kohno, Takako Sato, Satoshi Takakura, Kimiko Takei, Kaoru Inoue, Michiho Nishioka, Jun Yokota;
Mutation and expression of the DCC gene in human lung cancer.
Neoplasia 2:300-305(2000)

PubMed=11583962; DOI=10.1016/S0002-9440(10)62521-7; PMCID=PMC1850523
Nobuhiro Haruki, Tomoko Harano, Akira Masuda, Tohru Kiyono, Takao Takahashi, Yoshio Tatematsu, Shigeki Shimizu, Tetsuya Mitsudomi, Hiroyuki Konishi, Hirotaka Osada, Yoshitaka Fujii, Takashi Takahashi;
Persistent increase in chromosome instability in lung cancer: possible indirect involvement of p53 inactivation.
Am. J. Pathol. 159:1345-1352(2001)

PubMed=12794755; DOI=10.1002/ijc.11184
Hideki Endoh, Yasushi Yatabe, Shigeki Shimizu, Kohei Tajima, Hiroyuki Kuwano, Takashi Takahashi, Tetsuya Mitsudomi;
RASSF1A gene inactivation in non-small cell lung cancer and its clinical implication.
Int. J. Cancer 106:45-51(2003)

PubMed=14581340
Sana Yokoi, Kohichiroh Yasui, Toshihiko Iizasa, Issei Imoto, Takehiko Fujisawa, Johji Inazawa;
TERC identified as a probable target within the 3q26 amplicon that is detected frequently in non-small cell lung cancers.
Clin. Cancer Res. 9:4705-4713(2003)

PubMed=15185009; DOI=10.1007/s00262-004-0533-9; PMCID=PMC11034254
Haruko Yamaji, Toshihiko Iizasa, Eitetsu Koh, Makoto Suzuki, Mizuto Otsuji, Hao Chang, Shinichiro Motohashi, Sana Yokoi, Kenzo Hiroshima, Masatoshi Tagawa, Toshinori Nakayama, Takehiko Fujisawa;
Correlation between interleukin 6 production and tumor proliferation in non-small cell lung cancer.
Cancer Immunol. Immunother. 53:786-792(2004)

PubMed=15746151; DOI=10.1093/hmg/ddi092
Hiroto Izumi, Jun Inoue, Sana Yokoi, Hiroshi Hosoda, Tatsuhiro Shibata, Makoto Sunamori, Setsuo Hirohashi, Johji Inazawa, Issei Imoto;
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.
Hum. Mol. Genet. 14:997-1007(2005)

PubMed=17511773; DOI=10.1111/j.1349-7006.2007.00507.x; PMCID=PMC11159702
Takashi Fukuyama, Yoshinobu Ichiki, Sousuke Yamada, Yoshiki Shigematsu, Tetsuro Baba, Yoshika Nagata, Makiko Mizukami, Masakazu Sugaya, Mitsuhiro Takenoyama, Takeshi Hanagiri, Kenji Sugio, Kosei Yasumoto;
Cytokine production of lung cancer cell lines: correlation between their production and the inflammatory/immunological responses both in vivo and in vitro.
Cancer Sci. 98:1048-1054(2007)

PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846
Raquel Blanco, Reika Iwakawa, Mo-Ying Tang, Takashi Kohno, Barbara Angulo, Ruben Pio, Luis M. Montuenga, John D. Minna, Jun Yokota, Montse Sanchez-Cespedes;
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)

PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x; PMCID=PMC11158680
Reika Iwakawa, Takashi Kohno, Masatoshi Enari, Tohru Kiyono, Jun Yokota;
Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.
Cancer Sci. 101:1891-1896(2010)

PubMed=23381221; DOI=10.3892/or.2013.2266; PMCID=PMC3621652
Makoto Suzuki, Kenji Shiraishi, Ayami Eguchi, Koei Ikeda, Takeshi Mori, Kentaro Yoshimoto, Yasuomi Ohba, Tatsuya Yamada, Takaaki Ito, Yoshifumi Baba, Hideo Baba;
Aberrant methylation of LINE-1, SLIT2, MAL and IGFBP7 in non-small cell lung cancer.
Oncol. Rep. 29:1308-1314(2013)

PubMed=25120651; DOI=10.3892/ol.2014.2234; PMCID=PMC4114630
Makoto Suzuki, Koei Ikeda, Kenji Shiraishi, Ayami Eguchi, Takeshi Mori, Kentaro Yoshimoto, Hidekatsu Shibata, Takaaki Ito, Yoshifumi Baba, Hideo Baba;
Aberrant methylation and silencing of IRF8 expression in non-small cell lung cancer.
Oncol. Lett. 8:1025-1030(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7088
CGH-DB; 190-1
CGH-DB; 9175-4
Anatomy/cell type resources BTO; BTO_0004886
Chemistry resources ChEMBL-Cells; CHEMBL3307345
ChEMBL-Targets; CHEMBL614234
PubChem_Cell_line; CVCL_7088
Encyclopedic resources Wikidata; Q54938387
Experimental variables resources EFO; EFO_0002843
Polymorphism and mutation databases Cosmic; 713859
Cosmic; 801575
Cosmic; 844813
Cosmic; 876168
Cosmic; 917999
Cosmic; 929155
Cosmic; 1089228
Cosmic; 1219087
Cosmic; 1239915
Cosmic; 1571736
Cosmic; 2125280
Cosmic; 2668325
IARC_TP53; 2383
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number23