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Cellosaurus Nu61 (CVCL_7086)

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Cell line name Nu61
Synonyms NU61; nu61; nu61-8-4000
Accession CVCL_7086
Resource Identification Initiative To cite this cell line use: Nu61 (RRID:CVCL_7086)
Comments Characteristics: Established after 8 serial cycles of passage of the parental cell line in athymic nude mice and in vivo irradiation.
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Oral cavity, tongue, anterior part; UBERON=UBERON_0010032.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu542Lys (c.1624G>A); ClinVar=VCV000031944; Zygosity=Unspecified (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7118 (SCC-61)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=80
Publications

PubMed=14755057; DOI=10.1073/pnas.0308102100; PMCID=PMC341831
Nikolai N. Khodarev, Michael A. Beckett, Edwardine Labay, Thomas Darga, Bernard Roizman, Ralph R. Weichselbaum;
STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
Proc. Natl. Acad. Sci. U.S.A. 101:1714-1719(2004)

Cross-references
Encyclopedic resources Wikidata; Q54931151
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number17