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Cellosaurus RLA255-4 (CVCL_6C63)

[Text version]
Cell line name RLA255-4
Accession CVCL_6C63
Resource Identification Initiative To cite this cell line use: RLA255-4 (RRID:CVCL_6C63)
Comments Characteristics: At the permissive temperature (33 Celsius) expresses a transformed phenotype (rapid growth, high cell density, etc) and at the restrictive temperature (44 Celsius) expresses a non-transformed phenotype (slower growth, lower saturation density, etc).
Doubling time: 15 hours (PubMed=6248862).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA255).
Derived from site: In situ; Embryonic liver; UBERON=UBERON_0002107.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell Sex unspecified
Age at sampling 18FD
Category Transformed cell line
Publications

PubMed=6248862; DOI=10.1073/pnas.77.5.2731; PMCID=PMC349477
Schlegel-Haueter S.E., Schlegel W., Chou J.Y.
Establishment of a fetal rat liver cell line that retains differentiated liver functions.
Proc. Natl. Acad. Sci. U.S.A. 77:2731-2734(1980)

PubMed=2581111; DOI=10.1016/0076-6879(85)09104-2
Chou J.Y.
Establishment of rat fetal liver lines and characterization of their metabolic and hormonal properties: use of temperature-sensitive SV40 virus.
Methods Enzymol. 109:385-396(1985)

Cross-references
Encyclopedic resources Wikidata; Q54950591
Entry history
Entry creation23-Feb-2016
Last entry update10-Sep-2024
Version number9