Cellosaurus cell line RLA255-4 (CVCL

Cross-references
Cell line name	RLA255-4
Accession	CVCL_6C63
Resource Identification Initiative	To cite this cell line use: RLA255-4 (RRID:CVCL_6C63)
Comments	Characteristics: At the permissive temperature (33 Celsius) expresses a transformed phenotype (rapid growth, high cell density, etc) and at the restrictive temperature (44 Celsius) expresses a non-transformed phenotype (slower growth, lower saturation density, etc). Doubling time: 15 hours (PubMed=6248862). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA255). Derived from site: In situ; Embryonic liver; UBERON=UBERON_0002107.
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell	Sex unspecified
Age at sampling	18FD
Category	Transformed cell line
Publications	PubMed=6248862; DOI=10.1073/pnas.77.5.2731; PMCID=PMC349477 Susanna E. Schlegel-Haueter, Werner Schlegel, Janice Yang Chou; Establishment of a fetal rat liver cell line that retains differentiated liver functions. Proc. Natl. Acad. Sci. U.S.A. 77:2731-2734(1980) PubMed=2581111; DOI=10.1016/0076-6879(85)09104-2 Janice Yang Chou; Establishment of rat fetal liver lines and characterization of their metabolic and hormonal properties: use of temperature-sensitive SV40 virus. Methods Enzymol. 109:385-396(1985)
Encyclopedic resources	Wikidata; Q54950591
Entry history
Entry creation	23-Feb-2016
Last entry update	10-Sep-2024
Version number	9