ID   RLA255-4
AC   CVCL_6C63
DR   Wikidata; Q54950591
RX   PubMed=2581111;
RX   PubMed=6248862;
CC   Characteristics: At the permissive temperature (33 Celsius) expresses a transformed phenotype (rapid growth, high cell density, etc) and at the restrictive temperature (44 Celsius) expresses a non-transformed phenotype (slower growth, lower saturation density, etc).
CC   Doubling time: 15 hours (PubMed=6248862).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA255).
CC   Derived from site: In situ; Embryonic liver; UBERON=UBERON_0002107.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Sex unspecified
AG   18FD
CA   Transformed cell line
DT   Created: 23-02-16; Last updated: 10-09-24; Version: 9
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RX   PubMed=2581111; DOI=10.1016/0076-6879(85)09104-2;
RA   Chou J.Y.;
RT   "Establishment of rat fetal liver lines and characterization of their
RT   metabolic and hormonal properties: use of temperature-sensitive SV40
RT   virus.";
RL   Methods Enzymol. 109:385-396(1985).
//
RX   PubMed=6248862; DOI=10.1073/pnas.77.5.2731; PMCID=PMC349477;
RA   Schlegel-Haueter S.E., Schlegel W., Chou J.Y.;
RT   "Establishment of a fetal rat liver cell line that retains
RT   differentiated liver functions.";
RL   Proc. Natl. Acad. Sci. U.S.A. 77:2731-2734(1980).
//