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Cellosaurus SF188 (CVCL_6948)

[Text version]
Cell line name SF188
Synonyms SF-188; SF 188
Accession CVCL_6948
Resource Identification Initiative To cite this cell line use: SF188 (RRID:CVCL_6948)
Comments Doubling time: 26 hours (PubMed=19365568).
Omics: Transcriptomics; Microarray.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Brain, right frontal lobe; UBERON=UBERON_0002810.
Sequence variations
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D590 (SF-xL)
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
STR profile Source(s): Millipore=SCC282; PubMed=22570425; Technion Genomics Center

Markers:
AmelogeninX,Y
CSF1PO12
D1S165615,16
D2S44111
D2S133817,22
D3S135815,18
D5S81811,14
D7S8208,10
D8S117913,15
D10S124815
D12S39119
D13S31713
D16S53911
D18S5117
D19S43313,14
D21S1131
D22S104511,17
DYS39111
FGA22,22.2
Penta D14
Penta E10,13
TH019.3
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Web pages Provider; UCSF; -; https://web.archive.org/web/20150905213317/btrctissuecore.ucsf.edu/tbank/Cell_Line%20Notice.html
Publications

PubMed=3708752; DOI=10.1093/carcin/7.6.879
William J. Bodell, Toshimitsu Aida, Mitchel Stuart Berger, Mark Lester Rosenblum;
Increased repair of O6-alkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea.
Carcinogenesis 7:879-883(1986)

PubMed=2829496; DOI=10.1007/BF00686798
James T. Rutka, Jane R. Giblin, Dolores V. Dougherty, Hsiu-Chih Liu, John R. McCulloch, Carl W. Bell, Robert S. Stern, Charles Byron Wilson, Mark Lester Rosenblum;
Establishment and characterization of five cell lines derived from human malignant gliomas.
Acta Neuropathol. 75:92-103(1987)

DOI=10.1016/B978-0-12-333530-2.50005-8
Monica Nister, Bengt Westermark;
Human glioma cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay, Robert J. & Park, Jae-Gahb & Gazdar, Adi F. (eds.); pp.17-42; Academic Press; New York; USA (1994)

PubMed=9614553; DOI=10.1038/sj.gt.3300605
Mitsuhiro Tada, Shirou Sakuma, Richard D. Iggo, Hideyuki Saya, Yutaka Sawamura, Toshiyoshi Fujiwara, Jack Alan Roth;
Monitoring adenoviral p53 transduction efficiency by yeast functional assay.
Gene Ther. 5:339-344(1998)

DOI=10.1007/0-306-46861-1_11
Francis Ali-Osman;
Brain tumors.
(In book chapter) Human cell culture. Vol. 2. Cancer cell lines part 2; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.167-184; Kluwer Academic Publishers; New York; USA (1999)

PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x; PMCID=PMC8098486
Nobuaki Ishii, Daniel Maier, Adrian Merlo, Mitsuhiro Tada, Yutaka Sawamura, Annie-Claire Diserens, Erwin G. Van Meir;
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.
Brain Pathol. 9:469-479(1999)

PubMed=19033189; DOI=10.1073/pnas.0810199105; PMCID=PMC2596212
David R. Wise, Ralph J. DeBerardinis, Anthony Mancuso, Nabil Sayed, Xiao-Yong Zhang, Harla K. Pfeiffer, Ilana Nissim, Evgueni Daikhin, Marc Yudkoff, Steven B. McMahon, Craig B. Thompson;
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction.
Proc. Natl. Acad. Sci. U.S.A. 105:18782-18787(2008)

PubMed=19365568; DOI=10.1371/journal.pone.0005209; PMCID=PMC2666263
Dorine Arjanne Bax, Suzanne E. Little, Nathalie Gaspar, Lara Perryman, Lynley Marshall, Marta Viana-Pereira, Tania A. Jones, Richard D. Williams, Anita Grigoriadis, Gilles Vassal, Paul Workman ...Show all 16 authors... , Denise Sheer, Rui Manuel Reis, Andrew D.J. Pearson, Darren Hargrave, Chris Jones; Show fewer authors
Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.
PLoS ONE 4:e5209.1-e5209.9(2009)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844
Pierre Bady, Annie-Claire Diserens, Vincent Castella, Stefanie Kalt, Karl Heinimann, Marie-France Hamou, Mauro Delorenzi, Monika E. Hegi;
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

PubMed=25628092; DOI=10.1038/bjc.2015.16; PMCID=PMC4333505
Julia V. Cockle, Susan Picton, Jane Levesley, Elizabeth Jane Ilett, Angel Montero Carcaboso, Susan Short, L.P. Steel, Alan Melcher, Sean E. Lawler, Anke Bruning-Richardson;
Cell migration in paediatric glioma; characterisation and potential therapeutic targeting.
Br. J. Cancer 112:693-703(2015)

PubMed=29760046; DOI=10.1158/0008-5472.CAN-17-3691; PMCID=PMC6294442
Sharmistha Pal, David Kozono, Xiao-Dong Yang, Wojciech Fendler, Whitney Fitts, Jing Ni, John A. Alberta, Jean Zhao, Kevin X. Liu, Jie Bian, Nathalene Truffaux ...Show all 19 authors... , William Andrew Weiss, Adam C. Resnick, Pratiti Bandopadhayay, Keith Lloyd Ligon, Steven Gary DuBois, Sabine Mueller, Dipanjan Chowdhury, Daphne Adele Haas-Kogan; Show fewer authors
Dual HDAC and PI3K inhibition abrogates NFkappaB- and FOXM1-mediated DNA damage response to radiosensitize pediatric high-grade gliomas.
Cancer Res. 78:4007-4021(2018)

Cross-references
Cell line collections (Providers) Millipore; SCC282
Cell line databases/resources cancercelllines; CVCL_6948
Anatomy/cell type resources BTO; BTO_0002824
Chemistry resources ChEMBL-Cells; CHEMBL3307445
ChEMBL-Targets; CHEMBL614906
PubChem_Cell_line; CVCL_6948
Encyclopedic resources Wikidata; Q54952896
Experimental variables resources EFO; EFO_0022665
Gene expression databases GEO; GSM2197886
GEO; GSM2197887
GEO; GSM2197888
GEO; GSM2197889
GEO; GSM2197890
GEO; GSM2197891
Polymorphism and mutation databases Cosmic; 849884
Cosmic; 1875113
IARC_TP53; 5708
Progenetix; CVCL_6948
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number29