Cell line name |
HB611 |
Synonyms |
HB 611 |
Accession |
CVCL_6907 |
Resource Identification Initiative |
To cite this cell line use: HB611 (RRID:CVCL_6907) |
Comments |
Population: Japanese. Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
Sequence variations |
- Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly34Val (c.101G>T); ClinVar=VCV000017582; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Ala159Asp (c.476C>A); ClinVar=VCV001026335; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Asn239Asp (c.715A>G); ClinVar=VCV000234036; Zygosity=Heterozygous (from parent cell line).
|
Disease |
Hepatoblastoma (NCIt: C3728) Hepatoblastoma (ORDO: Orphanet_449) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_1296 (HuH-6 Clone 5) |
Sex of cell |
Male |
Age at sampling |
1Y |
Category |
Cancer cell line |
STR profile |
Source(s): CCRID
Markers:Amelogenin | X,Y |
CSF1PO | 10,11 |
D3S1358 | 14,17 |
D5S818 | 8,11 |
D7S820 | 11,12 |
D8S1179 | 10,11 |
D13S317 | 8,12 |
D16S539 | 10,11 |
D18S51 | 13,21 |
D21S11 | 29,30 |
FGA | 19,24 |
Penta D | 9,13 |
Penta E | 10,16 |
TH01 | 7,8 |
TPOX | 8 |
vWA | 14,17 |
Run an STR similarity search on this cell line |
Publications | PubMed=3025872; DOI=10.1073/pnas.84.2.444 Tsurimoto T., Fujiyama A., Matsubara K. Stable expression and replication of hepatitis B virus genome in an integrated state in a human hepatoma cell line transfected with the cloned viral DNA. Proc. Natl. Acad. Sci. U.S.A. 84:444-448(1987) PubMed=8389256; DOI=10.1093/carcin/14.5.987 Hsu I.C., Tokiwa T., Bennett W., Metcalf R.A., Welsh J.A., Sun T., Harris C.C. p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines. Carcinogenesis 14:987-992(1993) PubMed=7972006; DOI=10.1073/pnas.91.23.11045 Okamoto A., Demetrick D.J., Spillare E.A., Hagiwara K., Hussain S.P., Bennett W.P., Forrester K., Gerwin B.I., Serrano M., Beach D.H., Harris C.C. Mutations and altered expression of p16INK4 in human cancer. Proc. Natl. Acad. Sci. U.S.A. 91:11045-11049(1994) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_6907
CCRID; 1102HUM-NIFDC00072
|
Anatomy/cell type resources |
BTO; BTO:0001665
|
Encyclopedic resources |
Wikidata; Q54881366
|
Polymorphism and mutation databases |
Cosmic; 934553
Cosmic; 2668286
|
Entry history |
Entry creation | 04-Apr-2012 |
Last entry update | 05-Oct-2023 |
Version number | 18 |
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