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Cellosaurus HO-8910 (CVCL_6868)

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Cell line name HO-8910
Synonyms Ho-8910; HO8910; Ho8910
Accession CVCL_6868
Resource Identification Initiative To cite this cell line use: HO-8910 (RRID:CVCL_6868)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; CCRID). Originally thought to originate from the ascites of a 51 year old female patient with ovarian serous cystadenocarcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00606.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Transcriptomics; Microarray.
Miscellaneous: Formerly the CCRID database had 2 entries describing this cell line (3111C0001CCC000280, 3131C0001000700024). They were one of the sources for the STR profile of this entry.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_0310 (HO-8910PM)CVCL_B0WD (HO8910-TAX/CBP)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): CCRID; PubMed=26116706

Markers:
AmelogeninX
CSF1PO9,10 (PubMed=26116706)
10 (CCRID)
D2S133817
D3S135815,18
D5S81811,12 (PubMed=26116706)
12 (CCRID)
D6S104318
D7S8208,12 (PubMed=26116706)
12 (CCRID)
D8S117912 (CCRID)
12,13 (PubMed=26116706)
D12S39120,25
D13S31713.3
D16S5399,10
D18S5116 (CCRID)
16,17 (PubMed=26116706)
D19S43313 (CCRID)
13,14 (PubMed=26116706)
D21S1127,28
FGA18,21
Penta D8,15
Penta E7,17
TH017
TPOX8,12 (PubMed=26116706)
12 (CCRID)
vWA16,17,18 (CCRID)
16,18 (PubMed=26116706)

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=8082435
Han-Zhou Mou, Shen-Hua Xu, Yi-Yin Zhang, Li-Juan Qian, Xiao-Xi Huang, Chi-Hong Zhu, Yong-Liang Gao;
The establishment of human ovarian carcinoma cell line HO-8910 and its characteristics.
Zhonghua Fu Chan Ke Za Zhi 29:162-164(1994)

PubMed=11930655; DOI=10.3760/cma.j.issn.0366-6999.2002.01.107
Shen-Hua Xu, Han-Zhou Mou, Gui-Quan Lu, Chi-Hong Zhu, Zheng-Yan Yang, Yong-Liang Gao, Hong-Kun Lou, Xiang-Lin Liu, Yong Cheng, Wen Yang;
Gene expression profile differences in high and low metastatic human ovarian cancer cell lines by gene chip.
Chin. Med. J. 115:36-41(2002)

PubMed=25502083; DOI=10.1007/s12032-014-0426-5; PMCID=PMC4262766
Lian-Cheng Zhu, Zhen-Hua Hu, Juan-Juan Liu, Jian Gao, Bei Lin;
Gene expression profile analysis identifies metastasis and chemoresistance-associated genes in epithelial ovarian carcinoma cells.
Med. Oncol. 32:426.1-426.13(2015)

PubMed=26116706; DOI=10.1096/fj.14-266718
Fang Ye, Chu-Guang Chen, Jian Qin, Jie Liu, Cong-Yi Zheng;
Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.
FASEB J. 29:4268-4272(2015)

Cross-references
Anatomy/cell type resources BTO; BTO_0005438
Encyclopedic resources Wikidata; Q38151529
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23