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Cellosaurus QGY-7703 (CVCL_6715)

[Text version]
Cell line name QGY-7703
Synonyms QGY7703; QGY
Accession CVCL_6715
Resource Identification Initiative To cite this cell line use: QGY-7703 (RRID:CVCL_6715)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=28807831). Originally thought to originate from a 35 year old female patient with hepatocellular carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00552.
Population: African American.
Doubling time: 20.5 hours (PubMed=6280941).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3131C0001000700043). It was the sole source for the STR profile of this entry.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_M360 (QGY/cDDP)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): CCRID

Markers:
AmelogeninX
CSF1PO10
D2S133817
D3S135815,18
D5S81811,12
D7S82012
D8S117912
D13S31713.3
D16S5399,10
D18S5116
D19S43313
D21S1127,28
FGA18,21
TH017
TPOX12
vWA16,18

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

CLPUB00100
Zhu D.-H., Wang J.-B.
Establishment and comparison of non-malignant liver cell QSG-7701 and liver cancer cells.
Zhong Liu Fang Zhi Yan Jiu 5:7-9(1979)

PubMed=6280941
Wang J.-B., Zhu D.-H., Ye X.-Z., Chen R.-M.
Establishment and some characteristics of a hepatoma cell line (QGY-7703).
Zhonghua Zhong Liu Za Zhi 3:241-244(1981)

PubMed=10567879; DOI=10.1159/000030097
Luo D., Cheng S.C.-S., Xie H., Xie Y.
Chemosensitivity of human hepatocellular carcinoma cell line QGY-7703 is related to bcl-2 protein levels.
Tumor Biol. 20:331-340(1999)

PubMed=23505090; DOI=10.1002/hep.26402
Wang K., Lim H.Y., Shi S., Lee J., Deng S.-B., Xie T., Zhu Z., Wang Y.-L., Pocalyko D., Yang W.J., Rejto P.A., Mao M., Park C.-K., Xu J.-C.
Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma.
Hepatology 58:706-717(2013)

PubMed=28807831; DOI=10.1016/j.jhep.2017.08.002
Rebouissou S., Zucman-Rossi J., Moreau R., Qiu Z.-X., Hui L.-J.
Note of caution: contaminations of hepatocellular cell lines.
J. Hepatol. 67:896-897(2017)

Cross-references
Anatomy/cell type resources BTO; BTO:0005721
Chemistry resources ChEMBL-Cells; CHEMBL4295478
ChEMBL-Targets; CHEMBL4296490
PubChem_Cell_line; CVCL_6715
Encyclopedic resources Wikidata; Q54948825
Gene expression databases GEO; GSM936775
GEO; GSM1374839
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number25