ID   QGY-7703
AC   CVCL_6715
SY   QGY7703; QGY
DR   BTO; BTO:0005721
DR   ChEMBL-Cells; CHEMBL4295478
DR   ChEMBL-Targets; CHEMBL4296490
DR   GEO; GSM936775
DR   GEO; GSM1374839
DR   PubChem_Cell_line; CVCL_6715
DR   Wikidata; Q54948825
RX   CelloPub=CLPUB00100;
RX   PubMed=6280941;
RX   PubMed=10567879;
RX   PubMed=23505090;
RX   PubMed=28807831;
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=28807831). Originally thought to originate from a 35 year old female patient with hepatocellular carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00552.
CC   Population: African American.
CC   Doubling time: 20.5 hours (PubMed=6280941).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3131C0001000700043). It was the sole source for the STR profile of this entry.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): CCRID
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 12
ST   D8S1179: 12
ST   FGA: 18,21
ST   TH01: 7
ST   TPOX: 12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 25
RX   CelloPub=CLPUB00100;
RA   Zhu D.-H., Wang J.-B.;
RT   "Establishment and comparison of non-malignant liver cell QSG-7701 and
RT   liver cancer cells.";
RL   Zhong Liu Fang Zhi Yan Jiu 5:7-9(1979).
RX   PubMed=6280941;
RA   Wang J.-B., Zhu D.-H., Ye X.-Z., Chen R.-M.;
RT   "Establishment and some characteristics of a hepatoma cell line
RT   (QGY-7703).";
RL   Zhonghua Zhong Liu Za Zhi 3:241-244(1981).
RX   PubMed=10567879; DOI=10.1159/000030097;
RA   Luo D., Cheng S.C.-S., Xie H., Xie Y.;
RT   "Chemosensitivity of human hepatocellular carcinoma cell line QGY-7703
RT   is related to bcl-2 protein levels.";
RL   Tumor Biol. 20:331-340(1999).
RX   PubMed=23505090; DOI=10.1002/hep.26402;
RA   Wang K., Lim H.Y., Shi S., Lee J., Deng S.-B., Xie T., Zhu Z.,
RA   Wang Y.-L., Pocalyko D., Yang W.J., Rejto P.A., Mao M., Park C.-K.,
RA   Xu J.-C.;
RT   "Genomic landscape of copy number aberrations enables the
RT   identification of oncogenic drivers in hepatocellular carcinoma.";
RL   Hepatology 58:706-717(2013).
RX   PubMed=28807831; DOI=10.1016/j.jhep.2017.08.002;
RA   Rebouissou S., Zucman-Rossi J., Moreau R., Qiu Z.-X., Hui L.-J.;
RT   "Note of caution: contaminations of hepatocellular cell lines.";
RL   J. Hepatol. 67:896-897(2017).