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Cellosaurus NR6M (CVCL_6698)

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Cell line name NR6M
Accession CVCL_6698
Resource Identification Initiative To cite this cell line use: NR6M (RRID:CVCL_6698)
Comments Doubling time: 15.4 hours (PubMed=8845302).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3236; EGFR (Note=With p.Val30_Arg297del = EGFRvIII).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Swiss albino.
Hierarchy Parent: CVCL_6694 (NR-6)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=8845302
Surinder Kumar Batra, Shobha Castelino-Prabhu, Carol J. Wikstrand, Xiao-Pei Zhu, Peter A. Humphrey, Henry Seth Friedman, Darell Doty Bigner;
Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene.
Cell Growth Differ. 6:1251-1259(1995)

Cross-references
Encyclopedic resources Wikidata; Q54931018
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number17