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Cellosaurus NR-6 (CVCL_6694)

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Cell line name NR-6
Synonyms NR6
Accession CVCL_6694
Resource Identification Initiative To cite this cell line use: NR-6 (RRID:CVCL_6694)
Comments Characteristics: Does not express EGFR (PubMed=8845302).
Doubling time: 53.0 hours (PubMed=8845302).
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Swiss albino.
Hierarchy Parent: CVCL_0120 (3T3-Swiss albino)
Children:
CVCL_6695 (NR-6-R)CVCL_6698 (NR6M)CVCL_6699 (NR6V)
CVCL_6700 (NR6W)CVCL_XF60 (NR6WT)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=302945; DOI=10.1073/pnas.74.9.3918; PMCID=PMC431785
Rebecca Matteson Pruss, Harvey R. Herschman;
Variants of 3T3 cells lacking mitogenic response to epidermal growth factor.
Proc. Natl. Acad. Sci. U.S.A. 74:3918-3921(1977)

PubMed=3465719; DOI=10.1007/BF02621092
Angie Rizzino, Eric Ruff;
Fibroblast growth factor induces the soft agar growth of two non-transformed cell lines.
In Vitro Cell. Dev. Biol. 22:749-755(1986)

PubMed=8845302
Surinder Kumar Batra, Shobha Castelino-Prabhu, Carol J. Wikstrand, Xiao-Pei Zhu, Peter A. Humphrey, Henry Seth Friedman, Darell Doty Bigner;
Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene.
Cell Growth Differ. 6:1251-1259(1995)

Cross-references
Anatomy/cell type resources BTO; BTO_0001867
Encyclopedic resources Wikidata; Q54931006
Entry history
Entry creation04-Apr-2012
Last entry update27-Nov-2025
Version number15