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Cellosaurus MC/CAR-Z2 (CVCL_6671)

[Text version]
Cell line name MC/CAR-Z2
Synonyms MC-CAR-Z2; MNS-2
Accession CVCL_6671
Resource Identification Initiative To cite this cell line use: MC/CAR-Z2 (RRID:CVCL_6671)
Comments Group: Patented cell line.
Problematic cell line: Misclassified. Parent cell line (MC/CAR) was originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8147.
Population: Caucasian.
Doubling time: ~20-24 hours (ATCC=CRL-8147).
Selected for resistance to: ChEBI; CHEBI:63486; 8-azaguanine.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from sampling site: Peripheral blood.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000160364; Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1397 (MC/CAR)
Sex of cell Male
Age at sampling 81Y
Category Transformed cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81811,14,15
D7S8209,13
D13S31711,13
D16S53911,12
TH016,9
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Publications

Patent=US4647535
Ritts R.E. Jr.
Human nonsecretory plasmacytoid cell line.
Patent number US4647535, 03-Mar-1987

Cross-references
Cell line collections ATCC; CRL-8147
Cell line databases/resources CLO; CLO_0007576
Cell_Model_Passport; SIDM00635
Biological sample resources BioSample; SAMN03471194
Encyclopedic resources Wikidata; Q54904191
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number16