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Cellosaurus RAW 264.7 gammaNO(-) (CVCL_6517)

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Cell line name RAW 264.7 gammaNO(-)
Synonyms RAW 264.7 gamma NO(-)
Accession CVCL_6517
Resource Identification Initiative To cite this cell line use: RAW 264.7 gammaNO(-) (RRID:CVCL_6517)
Comments Characteristics: Unlike the parental cell line, does not produce nitric oxide upon treatment with interferon-gamma alone, but requires LPS for full activation (ATCC=CRL-2278).
Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_0493 (RAW 264.7)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-115,16
Mouse STR 1-217
Mouse STR 2-116
Mouse STR 3-214
Mouse STR 4-222.3,23.3
Mouse STR 5-514
Mouse STR 6-418
Mouse STR 6-712
Mouse STR 7-125.2
Mouse STR 8-113
Mouse STR 11-217
Mouse STR 12-116,17
Mouse STR 13-116.2
Mouse STR 15-322.3
Mouse STR 17-214,16
Mouse STR 18-318
Mouse STR 19-212,14
Mouse STR X-125

Run an STR similarity search on this cell line
Publications

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308
Jamie L. Almeida, Aleksandra Dakic, Karin Kindig, Maikan Kone, Deborah Lee Dormady Letham, Scott Langdon, Ruth Peat, Jayamalini Holding-Pillai, Erin M. Hall, Mark Ladd, Megan D. Shaffer ...Show all 23 authors... , Heath Berg, Jin-Liang Li, Georges Wigger, Steve Lund, Carolyn R. Steffen, Barbara B. Fransway, Bob Geraghty, Manuela Natoli, Beth A. Bauer, Susanne M. Gollin, Dale W. Lewis, Yvonne A. Reid; Show fewer authors
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:e0218412.1-e0218412.24(2019)

Cross-references
Cell line collections (Providers) ATCC; CRL-2278
Cell line databases/resources CLO; CLO_0008754
Biological sample resources BioSample; SAMN11397644
Encyclopedic resources Wikidata; Q54949248
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number17