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Cellosaurus 2B8 [Human Burkitt lymphoma] (CVCL_6354)

[Text version]
Cell line name 2B8 [Human Burkitt lymphoma]
Accession CVCL_6354
Resource Identification Initiative To cite this cell line use: 2B8 [Human Burkitt lymphoma] (RRID:CVCL_6354)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12569.
Population: African; Nigerian.
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr163His (c.487T>C); ClinVar=VCV000376680; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu287Ter (c.859G>T); Zygosity=Unspecified (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_W740 (HH514-16)
Children:
CVCL_3712 (HKB-11)
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
Publications

Patent=US6136599
Myung-Sam Cho;
Human hybrid host cell for mammalian gene expression.
Patent number US6136599, 24-Oct-2000

Cross-references
Cell line collections (Providers) ATCC; CRL-12569 - Discontinued
Cell line databases/resources CLO; CLO_0001246
cancercelllines; CVCL_6354
Cell_Model_Passport; SIDM01262
LINCS_LDP; LCL-2015
Encyclopedic resources Wikidata; Q54584309
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number31