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Cellosaurus HKB-11 (CVCL_3712)

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Cell line name HKB-11
Synonyms HKB11; Hybrid of Kidney and B cells-11
Accession CVCL_3712
Resource Identification Initiative To cite this cell line use: HKB-11 (RRID:CVCL_3712)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12568.
Doubling time: 41.0 +- 15.9 hours (Note=In serum-containing medium), 57.6 hours (Note=In FreeStyle medium), 48.1 hours (Note=In CDM4 medium) (PubMed=25822314).
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6354 (2B8 [Human Burkitt lymphoma])
Parent: CVCL_A784 (HEK293S)
Children:
CVCL_6345 (1G2 [Human hybrid])CVCL_6347 (20B8)
Category Hybrid cell line
STR profile Source(s): ATCC=CRL-12568

Markers:
AmelogeninX,Y
CSF1PO10,11,12
D5S8188,9,12
D7S82010,11,12
D13S31712,14
D16S5399,10
TH017,9,9.3
TPOX6,11
vWA15,16,19

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Publications

Patent=US6136599
Myung-Sam Cho;
Human hybrid host cell for mammalian gene expression.
Patent number US6136599, 24-Oct-2000

Patent=US6358703
Myung-Sam Cho, Sham-Yuen Chan, William Kelsey, Helena Yee;
Expression system for factor VIII.
Patent number US6358703, 19-Mar-2002

PubMed=12432229; DOI=10.1007/BF02254991
Myung-Sam Cho, Helena Yee, Sam Chan;
Establishment of a human somatic hybrid cell line for recombinant protein production.
J. Biomed. Sci. 9:631-638(2002)

PubMed=25822314; DOI=10.1007/s00449-015-1392-9
Rafael Tage Biaggio, Mario Soares de Abreu-Neto, Dimas Tadeu Covas, Kamilla Swiech;
Serum-free suspension culturing of human cells: adaptation, growth, and cryopreservation.
Bioprocess Biosyst. Eng. 38:1495-1507(2015)

Cross-references
Cell line collections (Providers) ATCC; CRL-12568 - Discontinued
Cell line databases/resources CLO; CLO_0003772
FCS-free; 175-2-331-1-4-3
Biological sample resources BioSample; SAMN03473641
Encyclopedic resources Wikidata; Q27555063
Experimental variables resources EFO; EFO_0022587
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number24