• Mutation; HGNC; HGNC:7883; NOTCH3; Simple; p.Gly289fs (c.866delG); Zygosity=Homozygous (PubMed=30737244).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg158Leu (c.473G>T); ClinVar=VCV000528248; Zygosity=Homozygous (PubMed=30737244).
  

PubMed=8121182; DOI=10.1002/jso.2930550209
Akira Yoshida, Tarou Asaga, Chihiro Masuzawa, Satoru Kawahara, Shunsuke Yanoma, Masaoki Harada, Takasi Okamoto;
Production of cytokines by thyroid carcinoma cell lines.
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PubMed=8176927; DOI=10.1002/jso.2930550308
Akira Yoshida, Tarou Asaga, Chihiro Masuzawa, Satoru Kawahara;
Alteration of tumorigenicity in undifferentiated thyroid carcinoma cells by introduction of normal chromosome 11.
J. Surg. Oncol. 55:170-174(1994)

PubMed=9177455; DOI=10.1016/S0304-3835(97)04742-3
Shoji Satake, Isamu Sugawara, M. Watanabe, Hiroshi Takami;
Lack of a point mutation of human DNA topoisomerase II in multidrug-resistant anaplastic thyroid carcinoma cell lines.
Cancer Lett. 116:33-39(1997)

PubMed=15613457; DOI=10.1677/erc.1.00818
Masahiko Onda, Mitsuru Emi, Akira Yoshida, S. Miyamoto, Junko Akaishi, Shin-ichi Asaka, Kosuke Mizutani, Kazuo Shimizu, Munehiko Nagahama, Kouichi Ito, Toshihiro Tanaka, Tatsuhiko Tsunoda;
Comprehensive gene expression profiling of anaplastic thyroid cancers with cDNA microarray of 25 344 genes.
Endocr. Relat. Cancer 11:843-854(2004)

PubMed=16924234; DOI=10.1038/sj.onc.1209899
Wei Yu, Issei Imoto, Jun Inoue, Masahiko Onda, Mitsuru Emi, Johji Inazawa;
A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity.
Oncogene 26:1178-1187(2007)

PubMed=18713817; DOI=10.1210/jc.2008-1102; PMCID=PMC2582569
Rebecca E. Schweppe, Joshua P. Klopper, Christopher T. Korch, Umarani Pugazhenthi, Miriam Benezra, Jeffrey A. Knauf, James Alexander Fagin, Laura A. Marlow, John Alton Copland 3rd, Robert Christian Smallridge, Bryan R. Haugen;
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.
J. Clin. Endocrinol. Metab. 93:4331-4341(2008)

Patent=US8029793
Akira Yoshida, Shunsuke Yanoma, Fumikazu Hirose;
Methods for inhibiting cell proliferation.
Patent number US8029793, 04-Oct-2011

PubMed=23833040; DOI=10.1210/jc.2013-2383; PMCID=PMC3763971
Inigo Landa, Ian Ganly, Timothy A. Chan, Norisato Mitsutake, Michiko Matsuse, Tihana Ibrahimpasic, Ronald A. Ghossein, James Alexander Fagin;
Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.
J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)

PubMed=30737244; DOI=10.1158/1078-0432.CCR-18-2953; PMCID=PMC6522280
Inigo Landa, Nikita Pozdeyev, Christopher T. Korch, Laura A. Marlow, Robert Christian Smallridge, John Alton Copland 3rd, Ying C. Henderson, Stephen Y. Lai, Gary L. Clayman, Naoyoshi Onoda, Aik-Choon Tan ...Show all 16 authors... , Maria E.R. Garcia-Rendueles, Jeffrey A. Knauf, Bryan R. Haugen, James Alexander Fagin, Rebecca E. Schweppe; Show fewer authors
Comprehensive genetic characterization of human thyroid cancer cell lines: a validated panel for preclinical studies.
Clin. Cancer Res. 25:3141-3151(2019)