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Cellosaurus FRO (CVCL_6287)

[Text version]
Cell line name FRO
Synonyms FRO81-2; Fro81-2; FRO 81-2
Accession CVCL_6287
Resource Identification Initiative To cite this cell line use: FRO (RRID:CVCL_6287)
Comments Omics: Transcriptome analysis by microarray.
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=18713817

Markers:
AmelogeninX,Y
D3S135817
D5S81810,14
D7S82012,13
D8S117913,14
D13S3179
D18S5112,15
D21S1128,30
FGA22
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=9348181; DOI=10.1210/endo.138.11.5509
Nishihara E., Nagayama Y., Mawatari F., Tanaka K., Namba H., Niwa M., Yamashita S.
Retrovirus-mediated herpes simplex virus thymidine kinase gene transduction renders human thyroid carcinoma cell lines sensitive to ganciclovir and radiation in vitro and in vivo.
Endocrinology 138:4577-4583(1997)

PubMed=11439348; DOI=10.1038/sj.onc.1204531
Frasca F., Vigneri P., Vella V., Vigneri R., Wang J.Y.-J.
Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to hepatocyte growth factor.
Oncogene 20:3845-3856(2001)

PubMed=15613457; DOI=10.1677/erc.1.00818
Onda M., Emi M., Yoshida A., Miyamoto S., Akaishi J., Asaka S., Mizutani K., Shimizu K., Nagahama M., Ito K., Tanaka T., Tsunoda T.
Comprehensive gene expression profiling of anaplastic thyroid cancers with cDNA microarray of 25 344 genes.
Endocr. Relat. Cancer 11:843-854(2004)

PubMed=16924234; DOI=10.1038/sj.onc.1209899
Yu W., Imoto I., Inoue J., Onda M., Emi M., Inazawa J.
A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity.
Oncogene 26:1178-1187(2007)

PubMed=18713817; DOI=10.1210/jc.2008-1102
Schweppe R.E., Klopper J.P., Korch C.T., Pugazhenthi U., Benezra M., Knauf J.A., Fagin J.A., Marlow L.A., Copland J.A. III, Smallridge R.C., Haugen B.R.
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.
J. Clin. Endocrinol. Metab. 93:4331-4341(2008)

PubMed=25675381; DOI=10.1210/jc.2014-2764
von Roemeling C.A., Marlow L.A., Pinkerton A.B., Crist A., Miller J., Tun H.W., Smallridge R.C., Copland J.A. III
Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target.
J. Clin. Endocrinol. Metab. 100:E697-E709(2015)

Cross-references
Cell line databases/resources CCRID; 3101HUMSCSP577
CGH-DB; 56-1
TOKU-E; 4067
Encyclopedic resources Wikidata; Q54835172
Polymorphism and mutation databases Cosmic; 685604
Cosmic; 849973
Cosmic; 918182
Cosmic; 931243
Cosmic; 990534
Cosmic; 1005457
Cosmic; 1094761
Cosmic; 1239981
Cosmic; 1699418
Cosmic; 2613251
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number17