ID   FRO
AC   CVCL_6287
SY   FRO81-2; Fro81-2; FRO 81-2
DR   CCRID; 3101HUMSCSP577
DR   CGH-DB; 56-1
DR   Cosmic; 685604
DR   Cosmic; 849973
DR   Cosmic; 918182
DR   Cosmic; 931243
DR   Cosmic; 990534
DR   Cosmic; 1005457
DR   Cosmic; 1094761
DR   Cosmic; 1239981
DR   Cosmic; 1699418
DR   Cosmic; 2613251
DR   TOKU-E; 4067
DR   Wikidata; Q54835172
RX   PubMed=9348181;
RX   PubMed=11439348;
RX   PubMed=15613457;
RX   PubMed=16924234;
RX   PubMed=18713817;
RX   PubMed=25675381;
CC   Omics: Transcriptomics; Microarray.
ST   Source(s): PubMed=18713817
ST   Amelogenin: X,Y
ST   D13S317: 9
ST   D18S51: 12,15
ST   D21S11: 28,30
ST   D3S1358: 17
ST   D5S818: 10,14
ST   D7S820: 12,13
ST   D8S1179: 13,14
ST   FGA: 22
ST   vWA: 16
DI   NCIt; C3878; Thyroid gland anaplastic carcinoma
DI   ORDO; Orphanet_142; Anaplastic thyroid carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 18
//
RX   PubMed=9348181; DOI=10.1210/endo.138.11.5509;
RA   Nishihara E., Nagayama Y., Mawatari F., Tanaka K., Namba H., Niwa M.,
RA   Yamashita S.;
RT   "Retrovirus-mediated herpes simplex virus thymidine kinase gene
RT   transduction renders human thyroid carcinoma cell lines sensitive to
RT   ganciclovir and radiation in vitro and in vivo.";
RL   Endocrinology 138:4577-4583(1997).
//
RX   PubMed=11439348; DOI=10.1038/sj.onc.1204531;
RA   Frasca F., Vigneri P., Vella V., Vigneri R., Wang J.Y.-J.;
RT   "Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile
RT   response to hepatocyte growth factor.";
RL   Oncogene 20:3845-3856(2001).
//
RX   PubMed=15613457; DOI=10.1677/erc.1.00818;
RA   Onda M., Emi M., Yoshida A., Miyamoto S., Akaishi J., Asaka S.-i.,
RA   Mizutani K., Shimizu K., Nagahama M., Ito K., Tanaka T., Tsunoda T.;
RT   "Comprehensive gene expression profiling of anaplastic thyroid cancers
RT   with cDNA microarray of 25 344 genes.";
RL   Endocr. Relat. Cancer 11:843-854(2004).
//
RX   PubMed=16924234; DOI=10.1038/sj.onc.1209899;
RA   Yu W., Imoto I., Inoue J., Onda M., Emi M., Inazawa J.;
RT   "A novel amplification target, DUSP26, promotes anaplastic thyroid
RT   cancer cell growth by inhibiting p38 MAPK activity.";
RL   Oncogene 26:1178-1187(2007).
//
RX   PubMed=18713817; DOI=10.1210/jc.2008-1102; PMCID=PMC2582569;
RA   Schweppe R.E., Klopper J.P., Korch C.T., Pugazhenthi U., Benezra M.,
RA   Knauf J.A., Fagin J.A., Marlow L.A., Copland J.A. 3rd, Smallridge R.C.,
RA   Haugen B.R.;
RT   "Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer
RT   cell lines reveals cross-contamination resulting in cell line
RT   redundancy and misidentification.";
RL   J. Clin. Endocrinol. Metab. 93:4331-4341(2008).
//
RX   PubMed=25675381; DOI=10.1210/jc.2014-2764; PMCID=PMC4422887;
RA   von Roemeling C.A., Marlow L.A., Pinkerton A.B., Crist A., Miller J.,
RA   Tun H.W., Smallridge R.C., Copland J.A. 3rd;
RT   "Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals
RT   stearoyl CoA desaturase 1 as a novel therapeutic target.";
RL   J. Clin. Endocrinol. Metab. 100:E697-E709(2015).
//