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Cellosaurus SK-RC-9 (CVCL_6174)

[Text version]
Cell line name SK-RC-9
Synonyms SK-RC-09; SK RC 09; SKRC-9; SK-RC9; SKRC9M
Accession CVCL_6174
Resource Identification Initiative To cite this cell line use: SK-RC-9 (RRID:CVCL_6174)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Miscellaneous: STR profile from MSKCC antibody and bioresource core facility.
Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; 12687; VHL; Simple; p.Leu89Arg (c.266T>G); Zygosity=Unspecified (PubMed=7915601).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): MSKCC


Run an STR similarity search on this cell line
Web pages https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-rc-m-metastatic-human-renal-cell-carcinoma-rcc-cell-line-collection

PubMed=479762; DOI=10.1084/jem.150.3.564
Ueda R., Shiku H., Pfreundschuh M., Takahashi T., Li L.T.C., Whitmore W.F. Jr., Oettgen H.F., Old L.J.
Cell surface antigens of human renal cancer defined by autologous typing.
J. Exp. Med. 150:564-579(1979)

PubMed=6946460; DOI=10.1073/pnas.78.8.5122
Ueda R., Ogata S.-I., Morrissey D.M., Finstad C.L., Szkudlarek J., Whitmore W.F. Jr., Oettgen H.F., Lloyd K.O., Old L.J.
Cell surface antigens of human renal cancer defined by mouse monoclonal antibodies: identification of tissue-specific kidney glycoproteins.
Proc. Natl. Acad. Sci. U.S.A. 78:5122-5126(1981)

PubMed=6864164; DOI=10.1084/jem.158.1.53
Houghton A.N., Brooks H., Cote R.J., Taormina M.C., Oettgen H.F., Old L.J.
Detection of cell surface and intracellular antigens by human monoclonal antibodies. Hybrid cell lines derived from lymphocytes of patients with malignant melanoma.
J. Exp. Med. 158:53-65(1983)

PubMed=6582512; DOI=10.1073/pnas.81.2.568
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

Ebert T., Bander N.H., Finstad C.L., Ramsawak R.D., Old L.J.
Establishment and characterization of human renal cancer and normal kidney cell lines.
Cancer Res. 50:5531-5536(1990)

PubMed=7915601; DOI=10.1038/ng0594-85
Gnarra J.R., Tory K., Weng Y., Schmidt L.S., Wei M.H., Li H., Latif F., Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.R., Florence C., Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H., Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B., Linehan W.M.
Mutations of the VHL tumour suppressor gene in renal carcinoma.
Nat. Genet. 7:85-90(1994)

PubMed=27993170; DOI=10.1186/s12943-016-0565-8
Brodaczewska K.K., Szczylik C., Fiedorowicz M., Porta C., Czarnecka A.M.
Choosing the right cell line for renal cell cancer research.
Mol. Cancer 15:83.1-83.15(2016)

Encyclopedic resources Wikidata; Q54954642
Polymorphism and mutation databases Cosmic; 737184
Cosmic; 972917
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number22