ID   SK-RC-9
AC   CVCL_6174
SY   SK-RC-09; SK RC 09; SKRC-9; SK-RC9; SKRC9M
DR   Cosmic; 737184
DR   Cosmic; 972917
DR   Wikidata; Q54954642
RX   PubMed=479762;
RX   PubMed=2386958;
RX   PubMed=6582512;
RX   PubMed=6864164;
RX   PubMed=6946460;
RX   PubMed=7915601;
RX   PubMed=27993170;
WW   https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-rc-m-metastatic-human-renal-cell-carcinoma-rcc-cell-line-collection
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Sequence variation: Mutation; HGNC; 12687; VHL; Simple; p.Leu89Arg (c.266T>G); Zygosity=Unspecified (PubMed=7915601).
CC   Miscellaneous: STR profile from MSKCC antibody and bioresource core facility.
CC   Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
ST   Source(s): MSKCC
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 9,14
ST   D16S539: 12,13
ST   D18S51: 18
ST   D19S433: 10,15
ST   D21S11: 30
ST   D2S1338: 23,25
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 8,11
ST   D8S1179: 13,15
ST   FGA: 20
ST   TH01: 6,9.3
ST   TPOX: 8
ST   vWA: 18,19
DI   NCIt; C9385; Renal cell carcinoma
DI   ORDO; Orphanet_217071; Renal cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 22
//
RX   PubMed=479762; DOI=10.1084/jem.150.3.564;
RA   Ueda R., Shiku H., Pfreundschuh M., Takahashi T., Li L.T.C.,
RA   Whitmore W.F. Jr., Oettgen H.F., Old L.J.;
RT   "Cell surface antigens of human renal cancer defined by autologous
RT   typing.";
RL   J. Exp. Med. 150:564-579(1979).
//
RX   PubMed=2386958;
RA   Ebert T., Bander N.H., Finstad C.L., Ramsawak R.D., Old L.J.;
RT   "Establishment and characterization of human renal cancer and normal
RT   kidney cell lines.";
RL   Cancer Res. 50:5531-5536(1990).
//
RX   PubMed=6582512; DOI=10.1073/pnas.81.2.568;
RA   Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.;
RT   "Cell surface antigens of human ovarian and endometrial carcinoma
RT   defined by mouse monoclonal antibodies.";
RL   Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984).
//
RX   PubMed=6864164; DOI=10.1084/jem.158.1.53;
RA   Houghton A.N., Brooks H., Cote R.J., Taormina M.C., Oettgen H.F.,
RA   Old L.J.;
RT   "Detection of cell surface and intracellular antigens by human
RT   monoclonal antibodies. Hybrid cell lines derived from lymphocytes of
RT   patients with malignant melanoma.";
RL   J. Exp. Med. 158:53-65(1983).
//
RX   PubMed=6946460; DOI=10.1073/pnas.78.8.5122;
RA   Ueda R., Ogata S.-i., Morrissey D.M., Finstad C.L., Szkudlarek J.,
RA   Whitmore W.F. Jr., Oettgen H.F., Lloyd K.O., Old L.J.;
RT   "Cell surface antigens of human renal cancer defined by mouse
RT   monoclonal antibodies: identification of tissue-specific kidney
RT   glycoproteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:5122-5126(1981).
//
RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//
RX   PubMed=27993170; DOI=10.1186/s12943-016-0565-8;
RA   Brodaczewska K.K., Szczylik C., Fiedorowicz M., Porta C.,
RA   Czarnecka A.M.;
RT   "Choosing the right cell line for renal cell cancer research.";
RL   Mol. Cancer 15:83.1-83.15(2016).
//