Cellosaurus JS2 TLR4-/- D299G/T399I (CVCL_5L05)
| Cell line name | JS2 TLR4-/- D299G/T399I |
|---|---|
| Synonyms | TLR4-/- D299G/T399I; TLR4-/- 299/399; TLR4-/- Dual SNP |
| Accession | CVCL_5L05 |
| Resource Identification Initiative | To cite this cell line use: JS2 TLR4-/- D299G/T399I (RRID:CVCL_5L05) |
| Comments | Knockout cell: Method=KO mouse; MGI; MGI:96824; Tlr4. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11850; TLR4 (Note=With p.Asp299Gly and p.Thr399Ile). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Liver; UBERON=UBERON_0002107. Cell type: Hepatic stellate cell; CL=CL_0000632. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6. |
| Hierarchy | Parent: CVCL_C7PK (JS2) |
| Sex of cell | Sex unspecified |
| Age at sampling | Age unspecified |
| Category | Transformed cell line |
| Publications | PubMed=19085953; DOI=10.1002/hep.22697; PMCID=PMC2891538 |
| Cross-references | |
| Cell line collections (Providers) | Kerafast; EMS403 |
| Encyclopedic resources | Wikidata; Q54972635 |
| Entry history | |
| Entry creation | 14-Dec-2015 |
| Last entry update | 19-Dec-2024 |
| Version number | 11 |