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Cellosaurus JS2 TLR4-/- WT (CVCL_5L02)

[Text version]
Cell line name JS2 TLR4-/- WT
Synonyms TLR4-/- WT
Accession CVCL_5L02
Resource Identification Initiative To cite this cell line use: JS2 TLR4-/- WT (RRID:CVCL_5L02)
Comments Knockout cell: Method=KO mouse; MGI; MGI:96824; Tlr4.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11850; TLR4.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatic stellate cell; CL=CL_0000632.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_C7PK (JS2)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=19085953; DOI=10.1002/hep.22697; PMCID=PMC2891538
Jin-Sheng Guo, Johnny Loke, Feng Zheng, Feng Hong, Steven Yea, Masayuki Fukata, Mirko Tarocchi, Olivia Tuason Abar, Hong-Jin Huang, John J. Sninsky, Scott Laurence Friedman;
Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Toll-like receptor 4 to hepatic stellate cell responses.
Hepatology 49:960-968(2009)

Cross-references
Cell line collections (Providers) Kerafast; EMS404
Encyclopedic resources Wikidata; Q54972638
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number10