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Cellosaurus HT-29-luc-D6 (CVCL_5J34)

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Cell line name HT-29-luc-D6
Accession CVCL_5J34
Resource Identification Initiative To cite this cell line use: HT-29-luc-D6 (RRID:CVCL_5J34)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Discontinued: Revvity/PerkinElmer; 119264; true.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0320 (HT-29)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line
Publications

PubMed=14713107; DOI=10.1023/B:CLIN.0000006815.49932.98
Darlene E. Jenkins, Yoko A. Oei, Yvette S. Hornig, Shang-Fan Yu, Joan M. Dusich, Tony Purchio, Pamela R. Contag;
Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis.
Clin. Exp. Metastasis 20:733-744(2003)

Cross-references
Cell line collections (Providers) Revvity/PerkinElmer; 119264
Cell line databases/resources cancercelllines; CVCL_5J34
Encyclopedic resources Wikidata; Q54896516
Entry history
Entry creation14-Dec-2015
Last entry update27-Nov-2025
Version number22