Cellosaurus cell line Emma-spleen (CVCL

Cellosaurus Emma-spleen (CVCL_5I29)

Cross-references
Cell line name	Emma-spleen
Synonyms	EmmaSpleen; EFS
Accession	CVCL_5I29
Resource Identification Initiative	To cite this cell line use: Emma-spleen (RRID:CVCL_5I29)
Comments	Doubling time: ~3 days (Kerafast=EMN011-FP). Omics: Transcriptomics; Microarray. Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Disease	Canine hemangiosarcoma (NCIt: C122783)
Species of origin	Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615) Breed/subspecies: Golden Retriever; VBO=VBO_0200610.
Originate from same individual	CVCL_0C96 ! Emma-brain
Sex of cell	Female
Age at sampling	9Y
Category	Cancer cell line
Publications	PubMed=24582862; DOI=10.1016/j.yexcr.2014.02.020; PMCID=PMC4256199 Jong-Hyuk Kim, Aric M. Frantz, Katie L. Anderson, Ashley J. Graef, Milcah C. Scott, Sally Robinson, Leslie C. Sharkey, Timothy D. O'Brien, Erin B. Dickerson, Jaime F. Modiano; Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment. Exp. Cell Res. 323:155-164(2014) PubMed=30601866; DOI=10.1371/journal.pone.0210297; PMCID=PMC6314605 Matthew Dowling, Jonathan Samuelson, Bahaa A. Fadl-Alla, Holly C. Pondenis, Mark Byrum, Anne M. Barger, Timothy M. Fan; Overexpression of prostate specific membrane antigen by canine hemangiosarcoma cells provides opportunity for the molecular detection of disease burdens within hemorrhagic body cavity effusions. PLoS ONE 14:e0210297.1-e0210297.20(2019)
Cell line collections (Providers)	Kerafast; EMN011-FP
Encyclopedic resources	Wikidata; Q54832288
Gene expression databases	GEO; GSM1122237
Entry history
Entry creation	14-Dec-2015
Last entry update	10-Apr-2025
Version number	14