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Cellosaurus Emma-brain (CVCL_0C96)

[Text version]
Cell line name Emma-brain
Synonyms EmmaBrain; Emma-HSA; Emma; EFB
Accession CVCL_0C96
Resource Identification Initiative To cite this cell line use: Emma-brain (RRID:CVCL_0C96)
Comments Doubling time: ~5-7 days (Kerafast=EMN010-FP).
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
Disease Canine hemangiosarcoma (NCIt: C122783)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Golden Retriever; VBO=VBO_0200610.
Originate from same individual CVCL_5I29 ! Emma-spleen
Sex of cell Female
Age at sampling 9Y
Category Cancer cell line
Publications

PubMed=19461996; DOI=10.1371/journal.pone.0005549; PMCID=PMC2680013
Tamburini B.A., Trapp S., Phang T.L., Schappa J.T., Hunter L.E., Modiano J.F.
Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed.
PLoS ONE 4:e5549.1-e5549.12(2009)

PubMed=24582862; DOI=10.1016/j.yexcr.2014.02.020; PMCID=PMC4256199
Kim J.-H., Frantz A.M., Anderson K.L., Graef A.J., Scott M.C., Robinson S., Sharkey L.C., O'Brien T.D., Dickerson E.B., Modiano J.F.
Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment.
Exp. Cell Res. 323:155-164(2014)

PubMed=28029283; DOI=10.2460/ajvr.78.1.69; PMCID=PMC5299388
Witter L.E., Gruber E.J., Lean F.Z.-X., Stokol T.
Evaluation of procoagulant tissue factor expression in canine hemangiosarcoma cell lines.
Am. J. Vet. Res. 78:69-79(2017)

PubMed=30601866; DOI=10.1371/journal.pone.0210297; PMCID=PMC6314605
Dowling M., Samuelson J., Fadl-Alla B.A., Pondenis H.C., Byrum M., Barger A.M., Fan T.M.
Overexpression of prostate specific membrane antigen by canine hemangiosarcoma cells provides opportunity for the molecular detection of disease burdens within hemorrhagic body cavity effusions.
PLoS ONE 14:e0210297.1-e0210297.20(2019)

Cross-references
Cell line collections (Providers) Kerafast; EMN010-FP
Encyclopedic resources Wikidata; Q54832287
Gene expression databases GEO; GSM1122236
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number18