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Cellosaurus Emma-brain (CVCL_0C96)

[Text version]
Cell line name Emma-brain
Synonyms EmmaBrain; Emma-HSA; Emma; EFB
Accession CVCL_0C96
Resource Identification Initiative To cite this cell line use: Emma-brain (RRID:CVCL_0C96)
Comments Doubling time: ~5-7 days (Kerafast=EMN010-FP).
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
Disease Canine hemangiosarcoma (NCIt: C122783)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Golden Retriever; VBO=VBO_0200610.
Originate from same individual CVCL_5I29 ! Emma-spleen
Sex of cell Female
Age at sampling 9Y
Category Cancer cell line
Publications

PubMed=19461996; DOI=10.1371/journal.pone.0005549; PMCID=PMC2680013
Beth A. Tamburini, Susan Trapp, Tzu Lip Phang, Jill T. Schappa, Lawrence E. Hunter, Jaime F. Modiano;
Gene expression profiles of sporadic canine hemangiosarcoma are uniquely associated with breed.
PLoS ONE 4:e5549.1-e5549.12(2009)

PubMed=24582862; DOI=10.1016/j.yexcr.2014.02.020; PMCID=PMC4256199
Jong-Hyuk Kim, Aric M. Frantz, Katie L. Anderson, Ashley J. Graef, Milcah C. Scott, Sally Robinson, Leslie C. Sharkey, Timothy D. O'Brien, Erin B. Dickerson, Jaime F. Modiano;
Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment.
Exp. Cell Res. 323:155-164(2014)

PubMed=28029283; DOI=10.2460/ajvr.78.1.69; PMCID=PMC5299388
Lauren E. Witter, Erika J. Gruber, Fabian Zhi-Xiang Lean, Tracy Stokol;
Evaluation of procoagulant tissue factor expression in canine hemangiosarcoma cell lines.
Am. J. Vet. Res. 78:69-79(2017)

PubMed=30601866; DOI=10.1371/journal.pone.0210297; PMCID=PMC6314605
Matthew Dowling, Jonathan Samuelson, Bahaa A. Fadl-Alla, Holly C. Pondenis, Mark Byrum, Anne M. Barger, Timothy M. Fan;
Overexpression of prostate specific membrane antigen by canine hemangiosarcoma cells provides opportunity for the molecular detection of disease burdens within hemorrhagic body cavity effusions.
PLoS ONE 14:e0210297.1-e0210297.20(2019)

Cross-references
Cell line collections (Providers) Kerafast; EMN010-FP
Encyclopedic resources Wikidata; Q54832287
Gene expression databases GEO; GSM1122236
Entry history
Entry creation10-Apr-2015
Last entry update10-Apr-2025
Version number18