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Cellosaurus hTERT-RPE1 mRuby-APC15 (CVCL_5F68)

[Text version]
Cell line name hTERT-RPE1 mRuby-APC15
Synonyms hTERT-RPE1/APC15; hTERT-RPE1 APC15
Accession CVCL_5F68
Resource Identification Initiative To cite this cell line use: hTERT-RPE1 mRuby-APC15 (RRID:CVCL_5F68)
Comments Characteristics: Tetracycline-inducible expression of APC15-IRES2-mRuby.
Transfected with: HGNC; 24531; ANAPC15.
Transfected with: HGNC; 11730; TERT.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transfected with: UniProtKB; Q8ISF8; Entacmaea quadricolor eqFP611 (modified to produce the bright RFP mRuby2).
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VP32 (hTERT-RPE1 FRT/TR)
Sex of cell Female
Age at sampling 1Y
Category Telomerase immortalized cell line

PubMed=21926987; DOI=10.1038/ncb2347
Mansfeld J., Collin P., Collins M.O., Choudhary J.S., Pines J.
APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.
Nat. Cell Biol. 13:1234-1243(2011)

Cell line collections (Providers) CancerTools; 151710
Ximbio; 151710
Encyclopedic resources Wikidata; Q54896634
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number12