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Cellosaurus KY-Rb (CVCL_5A05)

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Cell line name KY-Rb
Accession CVCL_5A05
Resource Identification Initiative To cite this cell line use: KY-Rb (RRID:CVCL_5A05)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_28680; Cytarabine (Arabinosylcytosine; Ara-C).
Derived from site: In situ; Brain, meninges; UBERON=UBERON_0010743.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000375871; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Adult acute myelomonocytic leukemia (NCIt: C7962)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1346 (KY821)
Sex of cell Male
Age at sampling 28Y
Category Cancer cell line
Publications

CLPUB00209
Toshio Kakihara;
The characterization of highly resistant human leukemic cell lines to 1-beta-D-arabinofuranosylcytosine.
Acta Med. Biol. 39:119-127(1991)

Cross-references
Cell line databases/resources cancercelllines; CVCL_5A05
Encyclopedic resources Wikidata; Q54900772
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number14