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Cellosaurus WT-CLS1 (CVCL_5904)

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Cell line name WT-CLS1
Synonyms CLS1
Accession CVCL_5904
Resource Identification Initiative To cite this cell line use: WT-CLS1 (RRID:CVCL_5904)
Comments Problematic cell line: Misclassified. Originally thought to be a Wilms tumor cell line but is a kidney rhabdoid tumor cell line (DOI=10.1002/cnr2.1110).
Population: Turkish.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
Disease Rhabdoid tumor of the kidney (NCIt: C8715)
Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
STR profile Source(s): CLS=300379

Markers:
AmelogeninX
CSF1PO11,13
D3S135814,19
D5S81811,12
D7S8208,10
D8S117913,14
D13S3179,11
D16S5399,11
D18S5113,15
D21S1130,31.2
FGA22,25
Penta D9
Penta E9,12
TH019,9.3
TPOX8
vWA15,19

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Publications

PubMed=20106868; DOI=10.1093/hmg/ddq042
Brigitte Royer-Pokora, Maike Anna Busch, Manfred Beier, Constanze Duhme, Carmen de Torres, Jaume Mora, Artur Brandt, Hans-Dieter Royer;
Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm.
Hum. Mol. Genet. 19:1651-1668(2010)

DOI=10.1002/cnr2.1110
Emily Kunce Stroup, Yunku Yeu, Albert Budhipramono, Tae Hyun Hwang, Dinesh Rakheja, Anat Erdreich-Epstein, Theodore Willis Laetsch, James F. Amatruda, Kenneth S. Chen;
WT-CLS1 is a rhabdoid tumor cell line and can be inhibited by miR-16.
Cancer Rep. 1:e1110.1-e1110.11(2018)

Cross-references
Cell line collections (Providers) CLS; 300379
Encyclopedic resources Wikidata; Q54994507
Polymorphism and mutation databases Cosmic; 1314022
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number18