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Cellosaurus PAC2 (CVCL_5853)

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Cell line name PAC2
Synonyms PAC-2
Accession CVCL_5853
Resource Identification Initiative To cite this cell line use: PAC2 (RRID:CVCL_5853)
Comments Group: Fish cell line.
Doubling time: ~36 hours (Note=At 28 Celsius), ~24 hours (Note=At 32 Celsius) (CelloPub=CLPUB00276).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI Taxonomy: 7955)
Sex of cell Sex unspecified
Age at sampling 2FD
Category Spontaneously immortalized cell line
Publications

CLPUB00276
Patricia A. Culp;
Random DNA integrations as an approach to insertional mutagenesis in the zebrafish (Brachydanio rerio).
Thesis PhD (1994); Massachusetts Institute of Technology; Cambridge; USA

PubMed=18377224; DOI=10.1089/zeb.2006.3.441
Shu-Ning He, Enrique Salas-Vidal, Saskia Rueb, S.F. Gabriel Krens, Annemarie H. Meijer, B. Ewa Snaar-Jagalska, Herman P. Spaink;
Genetic and transcriptome characterization of model zebrafish cell lines.
Zebrafish 3:441-453(2006)

PubMed=20147193; DOI=10.1101/pdb.prot5235
Niklas Senghaas, Reinhard W. Koster;
Culturing and transfecting zebrafish PAC2 fibroblast cells.
Cold Spring Harb. Protoc. 2009:Pdb.prot5235-Pdb.prot5235(2009)

PubMed=32990429; DOI=10.1021/acs.chemrestox.0c00315
Alena Tierbach, Ksenia J. Groh, Rene Schoenenberger, Kristin Schirmer, Marc Jean-Frederic Suter;
Characterization of the mercapturic acid pathway, an important phase II biotransformation route, in a zebrafish embryo cell line.
Chem. Res. Toxicol. 33:2863-2871(2020)

Cross-references
Cell line databases/resources Lonza; 1136
Encyclopedic resources Wikidata; Q54937415
Experimental variables resources EFO; EFO_0001224
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number17