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Cellosaurus LX-1 [Human HSC] (CVCL_5790)

[Text version]
Cell line name LX-1 [Human HSC]
Synonyms Lieming Xu-1
Accession CVCL_5790
Resource Identification Initiative To cite this cell line use: LX-1 [Human HSC] (RRID:CVCL_5790)
Comments Doubling time: 24 hours (PubMed=15591520).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRSV-T).
Anecdotal: Cell line name is derived from the name of the first author of the original paper.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatic stellate cell; CL=CL_0000632.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_5792 (LX-2)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=15591520; DOI=10.1136/gut.2004.042127; PMCID=PMC1774377
Lie-Ming Xu, Alex Y. Hui, Efsevia Albanis, Michael James Paul Arthur, Sheila M. O'Byrne, William S. Blaner, Piali Mukherjee, Scott Laurence Friedman, Francis J. Eng;
Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis.
Gut 54:142-151(2005)

PubMed=17760834; DOI=10.1111/j.1582-4934.2007.00060.x; PMCID=PMC3823251
Jens Herrmann, Axel M. Gressner, Ralf Weiskirchen;
Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function?
J. Cell. Mol. Med. 11:704-722(2007)

Cross-references
Anatomy/cell type resources BTO; BTO_0003515
Encyclopedic resources Wikidata; Q54903296
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number18