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Cellosaurus FRTL (CVCL_5753)

[Text version]
Cell line name FRTL
Synonyms FRT-L; FR-TL; Fischer Rat Thyroid in Low-serum
Accession CVCL_5753
Resource Identification Initiative To cite this cell line use: FRTL (RRID:CVCL_5753)
Comments Doubling time: 5-7 days (PubMed=1726925).
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Hierarchy Parent: CVCL_A6IE (FRT)
Children:
CVCL_A6II (FRT-L KiKi)CVCL_0265 (FRTL-5)CVCL_J436 (FRTL-Tc)
Sex of cell Sex unspecified
Age at sampling 6W
Category Spontaneously immortalized cell line
Publications

PubMed=391743; DOI=10.1016/S0074-7696(08)60619-1
Fransesco Saverio Ambesi-Impiombato, Hayden G. Coon;
Thyroid cells in culture.
Int. Rev. Cytol. Suppl. 10:163-172(1979)

PubMed=6106191; DOI=10.1073/pnas.77.6.3455; PMCID=PMC349635
Fransesco Saverio Ambesi-Impiombato, L.A.M. Parks, Hayden G. Coon;
Culture of hormone-dependent functional epithelial cells from rat thyroids.
Proc. Natl. Acad. Sci. U.S.A. 77:3455-3459(1980)

PubMed=6275984
Alfredo Fusco, Antonio Pinto, Donatella Tramontano, Gianfranco Tajana, Giancarlo Vecchio, Nobuo Tsuchida;
Block in the expression of differentiation markers of rat thyroid epithelial cells by transformation with Kirsten murine sarcoma virus.
Cancer Res. 42:618-626(1982)

PubMed=7042315; DOI=10.1210/endo-110-5-1790
Simona Fontana, Donatella Tramontano, Fransesco Saverio Ambesi-Impiombato, Guido Rossi;
Thyroglobulin production by rat thyroid cells in culture: a study at the level of single cells.
Endocrinology 110:1790-1795(1982)

PubMed=1726925
Hans Gerber, Hans-Jakob Peter, Lars Asmis, Hugo Studer;
Thyroid cell lines in research on goitrogenesis.
Thyroidology 3:115-118(1991)

Cross-references
Cell line collections (Providers) ATCC; CRL-1468 - Discontinued
CLS; 500202
Cell line databases/resources CLO; CLO_0003392
TOKU-E; 1281
Encyclopedic resources Wikidata; Q54835179
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number23