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Cellosaurus ZR-75-9a1 (CVCL_5613)

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Cell line name ZR-75-9a1
Accession CVCL_5613
Resource Identification Initiative To cite this cell line use: ZR-75-9a1 (RRID:CVCL_5613)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_41774; Tamoxifen.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0588 (ZR-75-1)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=2713239; DOI=10.1038/bjc.1989.107; PMCID=PMC2247166
Hendrik W. van den Berg, Maria Lynch, Jose Martin, John Nelson, Glenn R. Dickson, Alistair D. Crockard;
Characterisation of a tamoxifen-resistant variant of the ZR-75-1 human breast cancer cell line (ZR-75-9a1) and ability of the resistant phenotype.
Br. J. Cancer 59:522-526(1989)

Cross-references
Cell line databases/resources cancercelllines; CVCL_5613
Encyclopedic resources Wikidata; Q54996121
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number19