• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Homozygous (PubMed=9715273).
  

PubMed=7816807; DOI=10.1073/pnas.92.1.151; PMCID=PMC42835
Nikolai A. Lisitsyn, Natalia M. Lisitsina, Guido Dalbagni, Peter Barker, Carissa A. Sanchez, James R. Gnarra, William Marston Linehan, Brian J. Reid, Michael Howard Wigler;
Comparative genomic analysis of tumors: detection of DNA losses and amplification.
Proc. Natl. Acad. Sci. U.S.A. 92:151-155(1995)

PubMed=7824277
James Richard Eshleman, Evan Z. Lang, Gordana K. Bowerfind, Ramon Parsons, Bert Vogelstein, James K.V. Willson, Martina L. Veigl, Wallace David Sedwick, Sanford David Markowitz;
Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer.
Oncogene 10:33-37(1995)

PubMed=9715273; DOI=10.1038/sj.onc.1201986
James Richard Eshleman, Graham Casey, Mary E. Kochera, Wallace David Sedwick, Sandra E. Swinler, Martina L. Veigl, James K.V. Willson, Stuart Schwartz, Sanford David Markowitz;
Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53.
Oncogene 17:719-725(1998)