ID   VACO 576
AC   CVCL_5408
SY   VACO576; Vaco576; V576
DR   cancercelllines; CVCL_5408
DR   GEO; GSM784049
DR   IARC_TP53; 9387
DR   Progenetix; CVCL_5408
DR   Wikidata; Q54992775
RX   PubMed=7816807;
RX   PubMed=7824277;
RX   PubMed=9715273;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Homozygous (PubMed=9715273).
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
DI   NCIt; C2955; Colorectal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   46Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 16
//
RX   PubMed=7816807; DOI=10.1073/pnas.92.1.151; PMCID=PMC42835;
RA   Lisitsyn N.A., Lisitsina N.M., Dalbagni G., Barker P., Sanchez C.A.,
RA   Gnarra J.R., Linehan W.M., Reid B.J., Wigler M.H.;
RT   "Comparative genomic analysis of tumors: detection of DNA losses and
RT   amplification.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:151-155(1995).
//
RX   PubMed=7824277;
RA   Eshleman J.R., Lang E.Z., Bowerfind G.K., Parsons R., Vogelstein B.,
RA   Willson J.K.V., Veigl M.L., Sedwick W.D., Markowitz S.D.;
RT   "Increased mutation rate at the hprt locus accompanies microsatellite
RT   instability in colon cancer.";
RL   Oncogene 10:33-37(1995).
//
RX   PubMed=9715273; DOI=10.1038/sj.onc.1201986;
RA   Eshleman J.R., Casey G., Kochera M.E., Sedwick W.D., Swinler S.E.,
RA   Veigl M.L., Willson J.K.V., Schwartz S., Markowitz S.D.;
RT   "Chromosome number and structure both are markedly stable in RER
RT   colorectal cancers and are not destabilized by mutation of p53.";
RL   Oncogene 17:719-725(1998).
//